HRV and stress score changed a lot after first shot on Tuesday

JohnsonC

New Member
I started TRT on Tuesday. Got my first 250 mg testosterone shot. I'm wearing a garmin vivoactive 3 that measures BPM, sleep, stress etc. around the clock. After the shot on Tuesday my stress score has rised very significantly. Usually it's around 25-35. On Wednesday it was 50 and today it have been 48 (it's evening in my timezone now). It has never been this high before. It's based on HRV data. The graphs also look very different. I usually have some rest throughout the day, but now it's almost high or medium stress all day. My days looks the same, I'm not doing something more stressful than usual. Blood pressure haven't changed - it's around 110/80. But I do feel more stressed/wired. My resting heart rate is a bit higher than usual, but only a bit. Any idea why this stress score shot up like this?

I know it's a high dose but they give it every other week and I'm pretty sure it's some kind of depot. It's literally the only TRT clinic in the country, so I will have to start with their way of doing things but can split it up into weekly doses as soon as I start self injecting at home which I can switch to whenever I want.

Any inputs highly appreciated. In the only study I could find HRV scores got better and not worse on short-term TRT.
 

Attachments

  • IMG_9126.webp
    IMG_9126.webp
    51.7 KB · Views: 195
  • IMG_9127.webp
    IMG_9127.webp
    46 KB · Views: 184
Sounds like you already know the answer to your question - as you mentioned, 250mg is a large dose. Although I'm not familiar with the stress test device, high doses of test do seem to elevate heart rate and BP for a lot of guys.

You mentioned you can switch to self-injecting whenever you want. If I were you, I would do that ASAP and start with 50mg E3.5D (Monday AM and Thursday PM), for a total of 100mg/week, and go from there.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
6
Guests online
474
Total visitors
480

Latest posts

Back
Top