The more test you take and the larger the dosages per injection lowers shbg. It’s why guys with low shbg inject frequently. Higher dht lowers it also, danazol will tank it along with other dht derived steroids such as proviron and anavar. Trt should lower it in most men over time. Maybe I am biased but I feel having it shbg lower is more of a problem as opposed to elevatedHi guys. I've heard Boron can lower shgb but what about injection frequency ? Can doing more or less a week help ?
Actually it's the opposite, large infrequent injections hammers SHBG. That why it's recommended men with low SHBG avoid these types of protocols and inject smaller doses more frequently.IME more injections per week further lowers SHBG.
I know that’s the common wisdom, but I’ve gone back and forth between E3.5D, EOD, and ED injections over the past 4.5 years.Actually it's the opposite, large infrequent injections hammers SHBG. That why it's recommended men with low SHBG avoid these types of protocols and inject smaller doses more frequently.
You're an outlier.I know that’s the common wisdom, but I’ve gone back and forth between E3.5D, EOD, and ED injections over the past 4.5 years.
I consistently find that SHBG is lower on the more frequent injection schedules.
I have a few ideas as to why this may be the case for me, and do not mean to imply it will work for everyone as a rule, but it’s certainly worth a try.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
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A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038