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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
How bad of an idea would it be to give my wife some T-cyp?
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<blockquote data-quote="Nelson Vergel" data-source="post: 260426" data-attributes="member: 3"><p>Have you guys tried DHEA?</p><p></p><p>[URL unfurl="true"]https://www.sciencedirect.com/science/article/pii/S0531556520304587[/URL]</p><p></p><p><strong>Effects of DHEA Supplementation on Testosterone Levels</strong></p><p><strong></strong></p><p><strong>Summary:</strong></p><p></p><p>Dehydroepiandrosterone (DHEA) supplementation has been found to increase plasma testosterone levels in various subgroups. Specifically, the increment was higher in females, participants who received a higher dose (>50 mg/day) of DHEA, those who took the supplement for less than 12 weeks, healthy subjects, and younger participants (below 60 years old). However, the physiological or clinical significance of these increases remains unclear.</p><p></p><p>The greater increase in plasma testosterone levels in female recipients of DHEA supplements aligns with multiple studies. The levels of plasma testosterone significantly increase upon DHEA supplementation for women, especially those suffering from hypoactive sexual desire disorder, middle-age, and older women. The difference in testosterone level changes between male and female subjects can be attributed to the higher basal levels of testosterone in men.</p><p></p><p>A higher intake of DHEA supplement (>50 mg/day) theoretically results in a more significant increase in testosterone levels, provided that the testosterone biosynthesis pathways are not disrupted. However, it is worth noting that higher DHEA dosages could lead to undesirable side effects. Lastly, we hypothesize that older and unhealthy subjects, who may have genetic or metabolic disorders, might not fully restore the activity of testosterone biosynthesis merely by DHEA supplementation.</p><p></p><p><strong>References:</strong></p><p></p><ol> <li data-xf-list-type="ol">Casson et al., 1998</li> <li data-xf-list-type="ol">Malik et al., 2015</li> <li data-xf-list-type="ol">Morales et al., 2009</li> <li data-xf-list-type="ol">Poretsky et al., 2006</li> <li data-xf-list-type="ol">Villareal and Holloszy, 2004</li> <li data-xf-list-type="ol">Carruthers et al., 2007</li> <li data-xf-list-type="ol">Corona et al., 2013</li> <li data-xf-list-type="ol">Bloch et al., 2013</li> <li data-xf-list-type="ol">Collomp et al., 2018</li> <li data-xf-list-type="ol">Gurnell et al., 2008</li> <li data-xf-list-type="ol">Genazzani et al., 2011</li> <li data-xf-list-type="ol">Srinivasan et al., 2009</li> </ol></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 260426, member: 3"] Have you guys tried DHEA? [URL unfurl="true"]https://www.sciencedirect.com/science/article/pii/S0531556520304587[/URL] [B]Effects of DHEA Supplementation on Testosterone Levels Summary:[/B] Dehydroepiandrosterone (DHEA) supplementation has been found to increase plasma testosterone levels in various subgroups. Specifically, the increment was higher in females, participants who received a higher dose (>50 mg/day) of DHEA, those who took the supplement for less than 12 weeks, healthy subjects, and younger participants (below 60 years old). However, the physiological or clinical significance of these increases remains unclear. The greater increase in plasma testosterone levels in female recipients of DHEA supplements aligns with multiple studies. The levels of plasma testosterone significantly increase upon DHEA supplementation for women, especially those suffering from hypoactive sexual desire disorder, middle-age, and older women. The difference in testosterone level changes between male and female subjects can be attributed to the higher basal levels of testosterone in men. A higher intake of DHEA supplement (>50 mg/day) theoretically results in a more significant increase in testosterone levels, provided that the testosterone biosynthesis pathways are not disrupted. However, it is worth noting that higher DHEA dosages could lead to undesirable side effects. Lastly, we hypothesize that older and unhealthy subjects, who may have genetic or metabolic disorders, might not fully restore the activity of testosterone biosynthesis merely by DHEA supplementation. [B]References:[/B] [LIST=1] [*]Casson et al., 1998 [*]Malik et al., 2015 [*]Morales et al., 2009 [*]Poretsky et al., 2006 [*]Villareal and Holloszy, 2004 [*]Carruthers et al., 2007 [*]Corona et al., 2013 [*]Bloch et al., 2013 [*]Collomp et al., 2018 [*]Gurnell et al., 2008 [*]Genazzani et al., 2011 [*]Srinivasan et al., 2009 [/LIST] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
How bad of an idea would it be to give my wife some T-cyp?
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