Nelson Vergel
Founder, ExcelMale.com
Another study from Dr Lipshultz' group that links high IGF-1 with better erectile function while having no effect on the prostate.
Abstract
Growth hormone (GH) supplementation may help to preserve erectile function. We assessed whether serum insulin-like growth factor 1 (IGF-1) levels, a surrogate for GH levels, correlate with sexual function scores in 65 men who completed the Sexual Health Inventory for Men (SHIM) and Expanded Prostate Cancer Index Composite (EPIC) questionnaires, and had serum IGF-1 and testosterone levels determined. Median±s.d. IGF-1 level, SHIM and EPIC scores were 235.0±86.4, 19.5±8.7 and 56.4±28.3 mg ml[SUP]−1[/SUP], respectively. IGF-1 levels and total SHIM score correlate significantly (r=0.31, P=0.02), as do IGF-1 levels and all individual SHIM question scores, and IGF-1 levels and the sexual domain of the EPIC questionnaire (r=0.30, P=0.02). No correlation was observed between IGF-1 levels and Gleason score, IGF-1 and testosterone level or SHIM score and testosterone level. These data support a potential role for the GH axis in erectile function.
http://www.medscape.com/viewarticle/750510
Note:
IGF-1 is made in response to growth hormone and is needed for growth hormone to have its effects on muscles and other tissues. Growth hormone, synthesized in the pituitary gland, travels to the liver, which then responds by producing IGF-1.
The Food and Drug Administration has approved IGF-1 for children with a rare condition in which they fail to make enough of it. Their bones do not grow sufficiently and the children are very short. The drug, sold by Ipsen, is injected under the skin and travels through the blood to bones, stimulating them to grow.
Growth hormone replacement is being heavily regulated and monitored by the Drug Enforcement Agency (DEA) in the United States. It is only legally prescribed to men and women with growth hormone deficiency diagnosed via a growth hormone challenge test. Tests available are the insulin (ITT) test, the growth hormone releasing hormone-arginine test, and the glucagon test. If you are receiving GH from a physician who has not performed these tests, be aware that your treatment may be interrupted in the future if the physician is audited by the DEA.
Sermorelin is a growth hormone releasing hormone currently not regulated by the DEA since it cannot increase your growth hormone production beyond what is considered "normal".
Abstract
Growth hormone (GH) supplementation may help to preserve erectile function. We assessed whether serum insulin-like growth factor 1 (IGF-1) levels, a surrogate for GH levels, correlate with sexual function scores in 65 men who completed the Sexual Health Inventory for Men (SHIM) and Expanded Prostate Cancer Index Composite (EPIC) questionnaires, and had serum IGF-1 and testosterone levels determined. Median±s.d. IGF-1 level, SHIM and EPIC scores were 235.0±86.4, 19.5±8.7 and 56.4±28.3 mg ml[SUP]−1[/SUP], respectively. IGF-1 levels and total SHIM score correlate significantly (r=0.31, P=0.02), as do IGF-1 levels and all individual SHIM question scores, and IGF-1 levels and the sexual domain of the EPIC questionnaire (r=0.30, P=0.02). No correlation was observed between IGF-1 levels and Gleason score, IGF-1 and testosterone level or SHIM score and testosterone level. These data support a potential role for the GH axis in erectile function.
http://www.medscape.com/viewarticle/750510
Note:
IGF-1 is made in response to growth hormone and is needed for growth hormone to have its effects on muscles and other tissues. Growth hormone, synthesized in the pituitary gland, travels to the liver, which then responds by producing IGF-1.
The Food and Drug Administration has approved IGF-1 for children with a rare condition in which they fail to make enough of it. Their bones do not grow sufficiently and the children are very short. The drug, sold by Ipsen, is injected under the skin and travels through the blood to bones, stimulating them to grow.
Growth hormone replacement is being heavily regulated and monitored by the Drug Enforcement Agency (DEA) in the United States. It is only legally prescribed to men and women with growth hormone deficiency diagnosed via a growth hormone challenge test. Tests available are the insulin (ITT) test, the growth hormone releasing hormone-arginine test, and the glucagon test. If you are receiving GH from a physician who has not performed these tests, be aware that your treatment may be interrupted in the future if the physician is audited by the DEA.
Sermorelin is a growth hormone releasing hormone currently not regulated by the DEA since it cannot increase your growth hormone production beyond what is considered "normal".
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