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I don't think I'd do it with those numbers. When you calculate free testosterone with the Tru-T method you get 26 ng/dL, which is above mid-scale in the reference range of 16-31 ng/dL. Your free estradiol is a little on the low side, with a calculated value of about 0.4 pg/mL. The reference range is maybe 0.3-1.5 or so.

I'm sort of intrigued by the possibility of treating high SHBG with modest doses of ostarine, but you'd want to do it under guidance of an experienced practitioner, and recognize that it would still basically be an experimental therapy.

[QUOTE="Cataceous, post: 161892, member: 38109"] I don't think I'd do it with those numbers. When you calculate free testosterone with the Tru-T method you get 26 ng/dL, which is above mid-scale in the reference range of 16-31 ng/dL. Your free estradiol is a little on the low side, with a calculated value of about 0.4 pg/mL. The reference range is maybe 0.3-1.5 or so. I'm sort of intrigued by the possibility of treating high SHBG with modest doses of ostarine, but you'd want to do it under guidance of an experienced practitioner, and recognize that it would still basically be an experimental therapy. [/QUOTE]

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TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038