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I am going to get my estradiol tested three more times at regular intervals. Problem is here in the UK we don't have sensitive oestradiol test but I can still use them in comparison toone another to gauge wihich direction it is moving. I always thought that for having a tt of almost 3400, 45 pg oestradiol is pretty low especially considering I have low shbg. Whenever I took arimidex I ended up feeling very flat emotionally. Stronger errections possibly but still very insensitive.