High Free Testosterone and High Estradiol

[Diablo666]

Hi,

Is it possible to have Free testosterone above lab ranges and still having high E2?

My readings are

Total T 850
Free T 250
SHBG 19

Thanks for any insights. (btw, I am going to check my E2, but just curious if the above can give any indication or lead on what to expect).

 

[Vince Carter]

It is possible but no one can ascertain what your E could be. Make sure that you get the correct Estradiol LC/MS/MS test.

 

[get2dichoppa]

Hi,

Is it possible to have Free testosterone above lab ranges and still having high E2?

My readings are

Total T 850
Free T 250
SHBG 19

Thanks for any insights. (btw, I am going to check my E2, but just curious if the above can give any indication or lead on what to expect).

Absolutely is. On 30mg EOD my Free T was 34 (5-21 range) and my E2 was 60 (8-35 range). This usually happens with guys who have low SHBG. Although I didnt have mine tested i suspect it is low, meaning most of the T we inject is not binded (free) and converts rapidly to metabolites E2 and DHT. Feel like shit with this high of E2, so I backed down my dose a bit and added .25mg AI 1x per week. Still feeling like high & low E2 symptoms so I will have to do some bloodwork, starting to think TRT wont work for us low SHBG guys