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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
High estrogens / SHBG
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<blockquote data-quote="Castaneda" data-source="post: 141930" data-attributes="member: 36807"><p>This is right on the money and in line with what I have been thinking about these pathways.</p><p></p><p>Last night, I took 5mg Progesterone + 5mg DHEA in tocopherol. Everything went back to normal and I feel perfectly balanced today. Nothing remotely like yesterday. Too much DHEA is, indeed, a bad thing, you are absolutely right ... it doesn't take much at all to handle a "deficit". Again, a lab range doesn't always mean a deficit. The body is smarter than we are.</p><p></p><p>So for whatever reason, my body seems to like very small doses of Progesterone + DHEA on a semi-regular basis. I will try every night, but as soon as libido takes a nose dive, I'll back off to every other day. We all have to find that sweet spot, and labs really can't get us there. Experimentation seems to be the only way.</p><p></p><p>If I were to guess, when we go on TRT, the majority of us have a biofeedback loop that slows down conversion of Pregnenolone to the sex steroids, as the body is saying "I've got enough down here, stand down". So those of us that are eating higher fat in the diet (and lower carbs) will see cholesterol go up, because it's not being used for that pathway at the level it used to before exogenous T.</p><p></p><p>What I am curious about (and will likely test) is where are my Progesterone levels at? I have a feeling this is a blind spot for a lot of guys. They think Progesterone is a female hormone, but it plays an important role in male physiology as well and if it goes too low -- watch out. </p><p></p><p>Progesterone, if used properly is <a href="https://academic.oup.com/endo/article-abstract/24/3/351/2772525?redirectedFrom=fulltext" target="_blank">androgenic</a>. And consider this:</p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879672/" target="_blank">Testosterone and Progesterone, But Not Estradiol, Stimulate Muscle Protein Synthesis in Postmenopausal Women</a></p></blockquote><p></p>
[QUOTE="Castaneda, post: 141930, member: 36807"] This is right on the money and in line with what I have been thinking about these pathways. Last night, I took 5mg Progesterone + 5mg DHEA in tocopherol. Everything went back to normal and I feel perfectly balanced today. Nothing remotely like yesterday. Too much DHEA is, indeed, a bad thing, you are absolutely right ... it doesn't take much at all to handle a "deficit". Again, a lab range doesn't always mean a deficit. The body is smarter than we are. So for whatever reason, my body seems to like very small doses of Progesterone + DHEA on a semi-regular basis. I will try every night, but as soon as libido takes a nose dive, I'll back off to every other day. We all have to find that sweet spot, and labs really can't get us there. Experimentation seems to be the only way. If I were to guess, when we go on TRT, the majority of us have a biofeedback loop that slows down conversion of Pregnenolone to the sex steroids, as the body is saying "I've got enough down here, stand down". So those of us that are eating higher fat in the diet (and lower carbs) will see cholesterol go up, because it's not being used for that pathway at the level it used to before exogenous T. What I am curious about (and will likely test) is where are my Progesterone levels at? I have a feeling this is a blind spot for a lot of guys. They think Progesterone is a female hormone, but it plays an important role in male physiology as well and if it goes too low -- watch out. Progesterone, if used properly is [URL='https://academic.oup.com/endo/article-abstract/24/3/351/2772525?redirectedFrom=fulltext']androgenic[/URL]. And consider this: [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879672/']Testosterone and Progesterone, But Not Estradiol, Stimulate Muscle Protein Synthesis in Postmenopausal Women[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
High estrogens / SHBG
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