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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
High estrogens / SHBG
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<blockquote data-quote="Castaneda" data-source="post: 130501" data-attributes="member: 36807"><p>The anti-aging community puts optimal male estrogen at 20-30, though it's very individual. Some men feel awful with 20 while others thrive at that level. Mine is at 9 (using the sensitive assay), and I am concerned that Clomid could cause issues from blocking the effects of what little estrogen I have. And while estrone has lower binding affinity for estrogen receptors, just having a shit-load of it around would be enough to increase SHBG and take some T and E2 along with it. At least that's the theory I've been playing with.</p><p></p><p>Interesting side note --- I have been able to get transient surges of T (and libido) by putting an 850nm red LED light array on the testes. Nobody knows the long-term affects of this approach, but it's apparently stimulating mitochondria in Leydig cells. My concern would be potential for testicular cancer. Anyway, the reason I mention LLLT is because it looks like it functionally has the same effect as LH on Leydig cells, which is what HCG monotherapy would induce.</p><p></p><p>I could care less about spermatogenesis, as I have three kids. My baby-making days are done and over. This study would seem to indicate HCG could potentially lower SHBG (and raise free T and E2 which is what I need):</p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pubmed/6683724" target="_blank">Sex hormone-binding globulin changes with androgen replacement. - PubMed - NCBI</a></p></blockquote><p></p>
[QUOTE="Castaneda, post: 130501, member: 36807"] The anti-aging community puts optimal male estrogen at 20-30, though it's very individual. Some men feel awful with 20 while others thrive at that level. Mine is at 9 (using the sensitive assay), and I am concerned that Clomid could cause issues from blocking the effects of what little estrogen I have. And while estrone has lower binding affinity for estrogen receptors, just having a shit-load of it around would be enough to increase SHBG and take some T and E2 along with it. At least that's the theory I've been playing with. Interesting side note --- I have been able to get transient surges of T (and libido) by putting an 850nm red LED light array on the testes. Nobody knows the long-term affects of this approach, but it's apparently stimulating mitochondria in Leydig cells. My concern would be potential for testicular cancer. Anyway, the reason I mention LLLT is because it looks like it functionally has the same effect as LH on Leydig cells, which is what HCG monotherapy would induce. I could care less about spermatogenesis, as I have three kids. My baby-making days are done and over. This study would seem to indicate HCG could potentially lower SHBG (and raise free T and E2 which is what I need): [URL="https://www.ncbi.nlm.nih.gov/pubmed/6683724"]Sex hormone-binding globulin changes with androgen replacement. - PubMed - NCBI[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
High estrogens / SHBG
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