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In fertility clinics, some men are put om 5000+ IU a week.

I have been using hCG for 11 years and have not seen any decrease in efficacy. I know so since my testicles and sex drive remind me when I forget to inject. I use TRT of 75 mg T plus 500 IU hCG per week.  I notice that ED drugs or nitric oxide donors like citrulline make my testicles even fuller with that protocol.