Got my first bloods back

46and2

New Member
Got my blood test back today. Did the test last Wednesday, and I do my shot Thursday morning. Total T was 790 ng/dL, free T was 23.9 pg/mL. I was thinking we wanted to be a bit higher, 900 or above. E2 (sensitive) was off the charts low, < 3. It appears 1mg per week Anastrozole in divided doses is WAY too much. This might explain my sore joints, anxiety, irritability, and decreased sensitivity during sex. On the bad news side, total cholesterol was 226, so I have some work to do there. I will discuss the results next week with the doctor to see how we will modify my treatment. I plan to push for 2x weekly injections of 1/2 the total dosage, along with eliminating or severely reducing the Anastrozole. Not sure if we will stay at 160mg/week or not.
 
I think you have a good plan.

You're just one more example as to why most men don't need an AI.

What was your E2 levels that warranted the use of an AI anyways?

Two injections a week are just better for so many reasons.
 
I think you have a good plan.

You're just one more example as to why most men don't need an AI.

What was your E2 levels that warranted the use of an AI anyways?

Two injections a week are just better for so many reasons.

My E2 levels were OK before treatment, but when we tried a Clomid restart, my E2 had shot up significantly. My guess is Dr. Saya was trying to head that off before it started. My body just reacted very differently to Clomid versus exogenous testosterone.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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