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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Freeing Up Testosterone with Average T Levels and/or Higher SHBG
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<blockquote data-quote="Cataceous" data-source="post: 220561" data-attributes="member: 38109"><p>A modified thought experiment eliminates the distraction of the system perturbation: The step change in SHBG is accomplished by instantly removing the existing SHBG and replacing it with a higher/lower concentration of SHBG that is already bound to hormones at the correct rates to be at equilibrium with the existing free hormones. There should then be no pressure to change production rates. We've only increased or decreased total hormone levels. This is the no-change scenario I've been promoting. Shouldn't this be the case unless there actually is some independent mechanism by which SHBG affects HPTA feedback?</p></blockquote><p></p>
[QUOTE="Cataceous, post: 220561, member: 38109"] A modified thought experiment eliminates the distraction of the system perturbation: The step change in SHBG is accomplished by instantly removing the existing SHBG and replacing it with a higher/lower concentration of SHBG that is already bound to hormones at the correct rates to be at equilibrium with the existing free hormones. There should then be no pressure to change production rates. We've only increased or decreased total hormone levels. This is the no-change scenario I've been promoting. Shouldn't this be the case unless there actually is some independent mechanism by which SHBG affects HPTA feedback? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Freeing Up Testosterone with Average T Levels and/or Higher SHBG
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