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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Freeing Up Testosterone with Average T Levels and/or Higher SHBG
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<blockquote data-quote="DragonBits" data-source="post: 220480" data-attributes="member: 18023"><p>Cat?</p><p></p><p></p><p></p><p>Cat so what is your opinions of this 2020 NIH report?</p><p></p><p>"The level of SHBG was inversely proportional to BMI in both the untreated and the testosterone-treated men (Fig. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/figure/Fig1/" target="_blank">1</a>). The relationship between SHBG and total testosterone is shown for the untreated and T-treated men in Fig. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/figure/Fig2/" target="_blank">2</a>. <strong>As in previous analyses of results in eugonadal men [<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/#CR8" target="_blank">8</a>, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/#CR9" target="_blank">9</a>, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/#CR22" target="_blank">22</a>], the level of SHBG is highly positively correlated</strong> (<em>r</em> = 0.71, <em>p</em> < 0.01) with the total testosterone level in untreated men who presented for evaluation of AOH. <strong>On the other hand, there is no significant relationship between the levels of SHBG and total testosterone among men who were being treated with a transdermal testosterone preparation </strong>(Fig. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/figure/Fig2/" target="_blank">2</a>)."</p><p></p><p>[URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/[/URL]</p><p></p><p>Now my own tests results I did have higher shbg when my tot T was high, BUT that was only 2 examples a few months apart, and in total I only have 8 tests that included SHBG with Total T. Most of the time my shbg is between 35-45, but it did go up that time, BUT I was taking other hormones/supplements, T3/T4, preg and dhea, plus a month earlier I had been taking a prostate sup, so it would well have been any of those items that was really responsible for the increase in SHBG.</p><p></p><p>This also high lights another concern of mine, the vast majority of research is done on men NOT on TRT, while research on men on TRT is focused on finding problems(HCT, LDL, heart, etc), not on how various supplements/hormones interact.</p></blockquote><p></p>
[QUOTE="DragonBits, post: 220480, member: 18023"] Cat? Cat so what is your opinions of this 2020 NIH report? "The level of SHBG was inversely proportional to BMI in both the untreated and the testosterone-treated men (Fig. [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/figure/Fig1/']1[/URL]). The relationship between SHBG and total testosterone is shown for the untreated and T-treated men in Fig. [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/figure/Fig2/']2[/URL]. [B]As in previous analyses of results in eugonadal men [[URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/#CR8']8[/URL], [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/#CR9']9[/URL], [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/#CR22']22[/URL]], the level of SHBG is highly positively correlated[/B] ([I]r[/I] = 0.71, [I]p[/I] < 0.01) with the total testosterone level in untreated men who presented for evaluation of AOH. [B]On the other hand, there is no significant relationship between the levels of SHBG and total testosterone among men who were being treated with a transdermal testosterone preparation [/B](Fig. [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/figure/Fig2/']2[/URL])." [URL unfurl="true"]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526370/[/URL] Now my own tests results I did have higher shbg when my tot T was high, BUT that was only 2 examples a few months apart, and in total I only have 8 tests that included SHBG with Total T. Most of the time my shbg is between 35-45, but it did go up that time, BUT I was taking other hormones/supplements, T3/T4, preg and dhea, plus a month earlier I had been taking a prostate sup, so it would well have been any of those items that was really responsible for the increase in SHBG. This also high lights another concern of mine, the vast majority of research is done on men NOT on TRT, while research on men on TRT is focused on finding problems(HCT, LDL, heart, etc), not on how various supplements/hormones interact. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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Freeing Up Testosterone with Average T Levels and/or Higher SHBG
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