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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Freeing Up Testosterone with Average T Levels and/or Higher SHBG
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<blockquote data-quote="Cataceous" data-source="post: 220428" data-attributes="member: 38109"><p>However, it's not necessary to vary the testosterone production rate, because that rate is directly and proportionately determining free testosterone. In other words, even a guy on TRT who sees a reduction in SHBG does not experience a change in free testosterone if he maintains the same dose rate.</p><p></p><p></p><p>Yes.</p><p></p><p></p><p>Exactly. SERMs can do the job, but they can also reduce estrogenic activity where it's needed and increase it where it's not needed.</p><p></p><p>Guys on TRT can simply increase the dose to increase free testosterone. In theory you could have this paradoxical effect where in doing this the higher free testosterone pushes down SHBG enough that total testosterone actually decreases.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 220428, member: 38109"] However, it's not necessary to vary the testosterone production rate, because that rate is directly and proportionately determining free testosterone. In other words, even a guy on TRT who sees a reduction in SHBG does not experience a change in free testosterone if he maintains the same dose rate. Yes. Exactly. SERMs can do the job, but they can also reduce estrogenic activity where it's needed and increase it where it's not needed. Guys on TRT can simply increase the dose to increase free testosterone. In theory you could have this paradoxical effect where in doing this the higher free testosterone pushes down SHBG enough that total testosterone actually decreases. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Freeing Up Testosterone with Average T Levels and/or Higher SHBG
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