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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
First post. Can’t get E2 under control, starting to worry
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<blockquote data-quote="RobRoy" data-source="post: 277085" data-attributes="member: 42893"><p>Well, I can let you spend 10 years discovering. Why like I did. I could send you all the medical literature to tell you why. But let me summarize it real quick for you. When you apply transdermal testosterone you do increase serum DHT levels because of the five alpha reductase enzyme in the skin. You will significantly increase DHT levels in the serum with a transdermal approach compared to injecting testosterone. DHT has five times the binding capacity to SHBG than testosterone. So when you increase that serum DHT level significantly, it's going to bind the SHBG therefore, freeing up testosterone. That's why for any given number in the same man the cream will raise free testosterone levels better than injections. We see it clinically every single day of every single week. And so funny that you guys try to make things so complicated. The variable absorption of men is why we adjust dosage to each individual. We raise free testosterone levels in each man when we use a transdermal method by adjusting dosage accordingly. When you make a statement like you just did to try to imply intelligence on the subject, it just shows that men don't understand true physiology, and how simple this all can really be</p></blockquote><p></p>
[QUOTE="RobRoy, post: 277085, member: 42893"] Well, I can let you spend 10 years discovering. Why like I did. I could send you all the medical literature to tell you why. But let me summarize it real quick for you. When you apply transdermal testosterone you do increase serum DHT levels because of the five alpha reductase enzyme in the skin. You will significantly increase DHT levels in the serum with a transdermal approach compared to injecting testosterone. DHT has five times the binding capacity to SHBG than testosterone. So when you increase that serum DHT level significantly, it's going to bind the SHBG therefore, freeing up testosterone. That's why for any given number in the same man the cream will raise free testosterone levels better than injections. We see it clinically every single day of every single week. And so funny that you guys try to make things so complicated. The variable absorption of men is why we adjust dosage to each individual. We raise free testosterone levels in each man when we use a transdermal method by adjusting dosage accordingly. When you make a statement like you just did to try to imply intelligence on the subject, it just shows that men don't understand true physiology, and how simple this all can really be [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
First post. Can’t get E2 under control, starting to worry
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