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It's called Androgen receptor sensitivity. Some men can't tolerate a lot and they can make a little bit go long ways and others take a lot to go a little ways. It's as simple as finding the dose that improves the symptoms of the deficiency while avoiding any unwanted side effects. It's not aiming for any specific level and men or so caught up in numbers that they just can't understand that simple fact. If a level of 700 improve symptoms then that's the number and if the level is 1500 to resolve symptoms that's the number. But whatever number it is it has to be balanced against any unwanted side effects. No one should have to add any additional chemical or drug to control side effects no different then we didn't need to take any chemicals or drugs when we were teenagers or in our 20s when we had excellent testosterone levels. And the receptor saturation is not a theory it's proven in the medical literature, and in medical physiology. People just want to ignore physiology, but this receptor saturation is fully understood. The one thing that we haven't found, though is the saturation point in muscle tissue that's why bodybuilders are as big as they are.


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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