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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
First post. Can’t get E2 under control, starting to worry
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<blockquote data-quote="jmbb" data-source="post: 276836" data-attributes="member: 46555"><p>This is something I've always hypothesized about why a certain percentage of men might require estrogen control no matter what the dose is. Some guys just make more E2. Some make tons of DHT but almost no E2. On paper everything could look fine, but it could just be converting at an inappropriate ratio for the individual, especially if they're more sensitive to the range/ratio that the metabolites are present in.</p><p></p><p>I hate blanket statements, and one you hear from the anti-AI crowd a lot is "the body knows what to do with testosterone and will convert the exact amount of estradiol needed." This may be true in a completely normally functioning male, but with exogenous test in men with hormonal dysfunction, that's a pretty major assumption to be making.</p><p></p><p>I think the balance is going to be different for everybody, which is why its so important to be open minded to the range of what works in hormone therapy.</p></blockquote><p></p>
[QUOTE="jmbb, post: 276836, member: 46555"] This is something I've always hypothesized about why a certain percentage of men might require estrogen control no matter what the dose is. Some guys just make more E2. Some make tons of DHT but almost no E2. On paper everything could look fine, but it could just be converting at an inappropriate ratio for the individual, especially if they're more sensitive to the range/ratio that the metabolites are present in. I hate blanket statements, and one you hear from the anti-AI crowd a lot is "the body knows what to do with testosterone and will convert the exact amount of estradiol needed." This may be true in a completely normally functioning male, but with exogenous test in men with hormonal dysfunction, that's a pretty major assumption to be making. I think the balance is going to be different for everybody, which is why its so important to be open minded to the range of what works in hormone therapy. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
First post. Can’t get E2 under control, starting to worry
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