FDA Approves Pfizer Menopause Pill

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Nelson Vergel

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The drug is a once-daily pill that combines the female hormone estrogen with the drug bazedoxifene. The drug represents an alternative to older menopause pills that combined estrogen with another hormone: progestin, which has been linked to increased risk of lung and breast cancer.


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Like all hormone therapies, Pfizer says the new drug should be used for "the shortest duration" possible to relieve symptoms, due to the potential health risks. The New York-based drugmaker said it expects to launch the drug in the first quarter of 2014.

The drugs label states that Duavee should not be used by women with a history of blood clots or certain cancers, including cancer of the uterus and breast.

For decades, doctors believed hormone pills helped prevent heart problems and were good for bones and minds. That changed in 2002, when a big federal study was stopped because women taking estrogen-progestin pills had higher rates of cardiovascular disease and cancer.

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