Extracting Testosterone from Woolly Mammoth Hair

Jinzang

Member
I just found this interesting. Some researchers extracted testosterone from woolly mammoth hair. The article says:

The presence of testosterone in a pooled mammoth hair extract was confirmed with LC‐MS/MS using a similar sample preparation method as a recent study of cortisol in muskox. The hair pool was gently washed by water for 3 min, rinsed with HPLC grade isopropyl alcohol, dried by paper towel and placed in a fume hood overnight.
Mean male (n = 6) hair testosterone levels were 3.18 pg/mg hair, whereas female (n = 4) were 1.83 pg/mg hair (Fig. 2). Standard deviations were similar between the two sexes (1.26 in females vs 1.16 in males). Male minimum levels were more than twice those of females’ (1.86 pg/mg hair in males compared with 0.77 pg/mg hair in females) while maximal levels detected for a male was 4.57 pg/mg hair (vs 3.48 pg/mg hair for a female). High testosterone is typical of the third trimester pregnancy, and it is thus possible that females with high testosterone were pregnant.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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