Exercise Improves Hip Bone but Not Lumbar Bone Density in Chemically Castrated Men

Nelson Vergel

Founder, ExcelMale.com
Many men with prostate cancer receive androgen suppression therapy to decrease their testosterone to castrate levels. Those men what a lot of quality of life issues and body changes. They loss sex drive, have ED, loss bone density and lean mass, and gain fat. It is a very difficult patient population after cancer is treated since most doctors fear that giving them testosterone will fuel any potentially hidden cancer cells. This study shows that exercise may at least improve some of the bone mass lost in those men.






J Am Assoc Nurse Pract.
2013 Aug 27. doi: 10.1002/2327-6924.12066. [Epub ahead of print]
Self-reported exercise and bone mineral density in prostate cancer patients receiving androgen deprivation therapy.Mennen-Winchell LJ, Grigoriev V, Alpert P, Dos Santos H, Tonstad S.
[h=3]Source[/b]University Medical Center of Southern Nevada, Las Vegas, Nevada.

[h=3]Abstract[/b][h=4]PURPOSE:[/b]Men with prostate cancer receiving androgen deprivation therapy (ADT) are at increased risk for decreased bone mineral density (BMD). This study evaluates the relationship between self-reported daily activity, endurance and resistance exercise, and BMD measured by dual-energy x-ray absorptiometry (DEXA) in prostate cancer patients receiving ADT.
[h=4]DATA SOURCES:[/b]We recruited 96 men treated with ADT for ≥9 months from urology and cancer practices. The Canadian Fitness Survey assessed daily activity and exercise. Data on demographic and lifestyle characteristics and calcium and vitamin D supplementation were collected. Blood was collected for analysis of 25-OH vitamin D. A DEXA scan was performed.
[h=4]CONCLUSIONS:[/b]A positive association between endurance exercise and DEXA T-scores of the hip was shown. Regression analysis showed endurance exercise of medium to heavy intensity (measured as energy expenditure in MET-hours/week) was associated with T-scores of the hip (β = 0.048; 95% CI 0.003, 0.112; p = .040) but not with spinal T-scores after controlling for age, body mass index, and alcohol use.
[h=4]IMPLICATIONS FOR PRACTICE:[/b]Findings are cross-sectional, but if confirmed in prospective studies suggest that increased endurance exercise is a practical measure nurse practitioners can institute to prevent low bone density in the hip of men treated with ADT.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
0
Guests online
390
Total visitors
390

Latest posts

Back
Top