Estradiol

LVJR

New Member
Guys

If my E2 is 45.7 and I lower this by using an AI, would it be correct to assume that as my E2 lowers, my Free T and Total T would rise?
 
The conversion rate of testosterone to estradiol is around 0.2%. Unless you are not on TRT, testosterone does not increase much when anastrozole is added to TRT.

ECLIA Method. short for Electrochemiluminescent Immunoassay. It's a fast and affordable method to measure total testosterone and estradiol in your blood. Many labs use this method because it's automatic and doesn't require too much work on a lab technician's part. However, some studies have shown that values obtained with ECLIA are significantly higher compared to the more reliable LC/MS method.

LC/MS Method. LC/MS is short for liquid chromatography-mass spectrometry. It's considered the gold standard method by many researchers in measuring small molecules. Its accuracy and consistency is why the CDC is recommending LC/MS to be the standard method used when testing total testosterone and estradiol. While it's more accurate and sensitive, the LC/MS method is more expensive than ECLIA. And it takes a bit longer to get your results. Test number:
Estradiol, LCMS, Endo Sci
Labcorp test# 500108
 
My blood work in April gave me a reading of 1800 on testosterone and a 92! on estradiol. High numbers I know. I'm ready to just start over from scratch and get this thing working for me. I mentioned HCG to my doc but he has not yet given me a script for it. He said he would address this in July. Should there be an urgency to address this sooner? I'm injecting myself twice a week with 1/2 cc of testosterone cypionate. So obviously, the testosterone is converting into estrogen and probably should be lowered. I would hope that HCG would help too if keeping the same level of testosterone injection. In any case I need to have my homework done to counter my docs ignorance on the subject. Otherwise I need to see a hormonal specialist. I don't pretend to have the knowledge that you all have on this .. however I don't think the docs are well educated on this subject. I've been seeing this doc for over 12 years now and we have a good relationship.
 
My blood work in April gave me a reading of 1800 on testosterone and a 92! on estradiol. High numbers I know. I'm ready to just start over from scratch and get this thing working for me. I mentioned HCG to my doc but he has not yet given me a script for it. He said he would address this in July. Should there be an urgency to address this sooner? I'm injecting myself twice a week with 1/2 cc of testosterone cypionate. So obviously, the testosterone is converting into estrogen and probably should be lowered. I would hope that HCG would help too if keeping the same level of testosterone injection. In any case I need to have my homework done to counter my docs ignorance on the subject. Otherwise I need to see a hormonal specialist. I don't pretend to have the knowledge that you all have on this .. however I don't think the docs are well educated on this subject. I've been seeing this doc for over 12 years now and we have a good relationship.


Jonathanb - You are hijacking LVJR's thread.

Start your own and we will jump in to help you.

Thanks.

Gene
 
Not at all familiar with how to do this .. I don't see where I can start a thread. Not intentional of course my apologies.

Go to the main forum page. Click on Testosterone Q&A when in the forum at the top there is a button that says "Start a New Thread" it's that easy.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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