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If you've been taking .5mg of anastrozole on an EOD basis for "quite a while" I can assure you...your estradiol level is likely to be very, very low. I have to question the care you're receiving, at least I question it based on the few details in your post. As johndoesmith indicated, it would help if you posted the details of your protocol and your lab results. You're sure to generate a good discussion.