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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Erection quality issues
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<blockquote data-quote="Cataceous" data-source="post: 171929" data-attributes="member: 38109"><p>I agree with [USER=38443]@wondering[/USER] that plasma levels of testosterone should start rising very soon after an injection. I'm going to diverge on the question of when the peak occurs. I suspect it is most likely in the range of 2-8 hours post-injection, and almost certainly in under 12 hours. I base this on research, theory and my own results.</p><p></p><p>In particular, <a href="https://link.springer.com/chapter/10.1007/978-3-642-72185-4_11" target="_blank">some work by Behre and Nieschlag</a> is already consistent with peaks occurring in less than a day for propionate and enanthate. Here's the curve for enanthate:</p><p></p><p>[ATTACH=full]9255[/ATTACH]</p><p>The theory is easily illustrated with the simple bi-exponential model. There are two parameters to set: the half-life for the absorption, something like five days for cypionate, and the half-life for the elimination of testosterone in serum, which is estimated to be in the range of 10-100 minutes. For the latter, I'm partial to a figure of 30 minutes, but even if 100 minutes is used the peaks still occur in the first few hours. Here's a sample I ran for propionate with a little different model for absorption, but still with an apparent absorption half-life of about 0.8 days, and T usage half-life of 30 minutes. This is a step further, summing results to show what each day looks like with daily injections.</p><p>[ATTACH=full]9256[/ATTACH]</p><p>My limited measurements with daily propionate have at least been consistent with this model. I had taken several trough measurements, coming back in range of 300-500 ng/dL, depending on dose. Based on these I predicted a peak of roughly 1,100 ng/dL for a particular dose. Then I took a measurement at two hours post-injection, which was 1,000 ng/dl. While this single measurement is not too meaningful, it at least supports the idea of a rapid rise in serum testosterone.</p><p></p><p>I just recalled that [USER=38377]@bp[/USER] recently shared similar results <a href="https://www.excelmale.com/forum/threads/nandrolone-added-to-trt-to-reduce-dht.20537/post-171802" target="_blank">here</a> for his daily propionate injections.</p><p style="margin-left: 20px"><em>Protocol was :</em></p> <p style="margin-left: 20px"><em>70mg/week (propionate) ED injection (10mg /day)</em></p> <p style="margin-left: 20px"><em>Bloodwork was mental tbh.</em></p> <p style="margin-left: 20px"><em>My daily deviation was massive.</em></p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px"><em>TT:1100 (at 10.00, 2 hours after pin)</em></p> <p style="margin-left: 20px"><em>TT:350 (08:00 , 2 hours before pin)</em></p></blockquote><p></p>
[QUOTE="Cataceous, post: 171929, member: 38109"] I agree with [USER=38443]@wondering[/USER] that plasma levels of testosterone should start rising very soon after an injection. I'm going to diverge on the question of when the peak occurs. I suspect it is most likely in the range of 2-8 hours post-injection, and almost certainly in under 12 hours. I base this on research, theory and my own results. In particular, [URL='https://link.springer.com/chapter/10.1007/978-3-642-72185-4_11']some work by Behre and Nieschlag[/URL] is already consistent with peaks occurring in less than a day for propionate and enanthate. Here's the curve for enanthate: [ATTACH=full]9255[/ATTACH] The theory is easily illustrated with the simple bi-exponential model. There are two parameters to set: the half-life for the absorption, something like five days for cypionate, and the half-life for the elimination of testosterone in serum, which is estimated to be in the range of 10-100 minutes. For the latter, I'm partial to a figure of 30 minutes, but even if 100 minutes is used the peaks still occur in the first few hours. Here's a sample I ran for propionate with a little different model for absorption, but still with an apparent absorption half-life of about 0.8 days, and T usage half-life of 30 minutes. This is a step further, summing results to show what each day looks like with daily injections. [ATTACH=full]9256[/ATTACH] My limited measurements with daily propionate have at least been consistent with this model. I had taken several trough measurements, coming back in range of 300-500 ng/dL, depending on dose. Based on these I predicted a peak of roughly 1,100 ng/dL for a particular dose. Then I took a measurement at two hours post-injection, which was 1,000 ng/dl. While this single measurement is not too meaningful, it at least supports the idea of a rapid rise in serum testosterone. I just recalled that [USER=38377]@bp[/USER] recently shared similar results [URL='https://www.excelmale.com/forum/threads/nandrolone-added-to-trt-to-reduce-dht.20537/post-171802']here[/URL] for his daily propionate injections. [INDENT][I]Protocol was :[/I][/INDENT] [INDENT][I]70mg/week (propionate) ED injection (10mg /day)[/I][/INDENT] [INDENT][I]Bloodwork was mental tbh.[/I][/INDENT] [INDENT][I]My daily deviation was massive.[/I][/INDENT] [INDENT][I][/I][/INDENT] [INDENT][I]TT:1100 (at 10.00, 2 hours after pin)[/I][/INDENT] [INDENT][I]TT:350 (08:00 , 2 hours before pin)[/I][/INDENT] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Erection quality issues
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