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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
ED, No Libido, Seeing A Urologist Now
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<blockquote data-quote="madman" data-source="post: 194998" data-attributes="member: 13851"><p>Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects.</p><p></p><p>As I stated earlier when using exogenous esterified T there will be an initial burst release and T levels start rising within the first few hours and true peak when using the most commonly prescribed esters (TC/TE) will be 8-12 hrs post-injection/elevated during the first few days.</p><p></p><p>When on trt we test at the true trough and as we want to see where your levels sit (lowest point) to make sure TT/FT levels are not too low or high which could lead to lack of relief low-t symptoms/side-effects.</p><p></p><p>Blood work is important and using accurate assays is critical.</p><p></p><p>As you can see your trough TT sits in the 800s and your FT is high which would mean that your peak TT/FT levels will be much higher!</p><p></p><p>Unfortunately you a relying on the calculated FT let alone we have no idea if your TT was tested using LC/MS-MS.</p><p></p><p>The only way to know where your FT level truly sits on such protocol (dose T/injection frequency) is to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration.</p><p></p><p>Let alone TT would need to be tested using (LC/MS-MS) even when using calculated methods.</p><p></p><p>Regardless you can be rest assured that with a TT 800s and seeing as you have low SHBG 14 nmol/L that your FT will be high.</p><p></p><p>If anything you should have labs done again and make sure to use the most accurate assays as you may be surprised that your FT level may very well be much higher than you think.</p><p></p><p></p><p>When testing your FT either one will suffice!</p><p></p><p>1. <a href="https://www.discountedlabs.com/hematocrit-total-and-free-testosterone-1500-ng-dl" target="_blank">Testosterone, Total and Free (NO Upper Limit) plus Hematocrit</a></p><p></p><p>2. <a href="https://www.discountedlabs.com/testosterone-free-dialysis-and-total-ls-ms-ms" target="_blank">Testosterone, Total, LC/MS and Free (Equilibrium Ultrafiltration)</a></p><p></p><p></p><p></p><p></p><p></p><p>I would also test your free estradiol (LC/MS-MS).</p><p></p><p>[URL unfurl="true"]https://www.discountedlabs.com/free-estradiol-sensitive[/URL]</p><p></p><p></p><p></p><p></p><p></p><p>From your post #10.</p><p></p><p><strong>And for people who are curious... <u>yes I donate blood every 58 days. Hard to believe but I'm going for my 8th straight donation without skipping any additional days</u>. I spoke to my Hematologist and asked him if this was safe? He said... he doesn't see anything wrong with it. So... <u>I donate 6 times a year. Yes, I feel like sh#$ for about 7-8 days (after each donation...) but... if you want to live... what else can you do</u>?</strong></p><p></p><p>Not sure where your RBCs/hemoglobin/hematocrit sit on your current protocol (65 mg T E4D) but it is most likely high due to your high FT.</p><p></p><p>Again even though your TT 800 may not seem absurdly high seeing as you have low SHBG 14 nmol/L you can rest assured that your FT is high.</p><p></p><p>I would take a step back and think deeply on this as donating frequently is a surefire way to crash your ferritin.</p><p></p><p>Many get caught up in that constantly donating merry go round to control hematocrit only to end up crashing ferritin/iron which can lead to many other issues.</p><p></p><p>I would look into injecting more frequently as in daily or EOD using a lower dose of T.</p></blockquote><p></p>
[QUOTE="madman, post: 194998, member: 13851"] Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects. As I stated earlier when using exogenous esterified T there will be an initial burst release and T levels start rising within the first few hours and true peak when using the most commonly prescribed esters (TC/TE) will be 8-12 hrs post-injection/elevated during the first few days. When on trt we test at the true trough and as we want to see where your levels sit (lowest point) to make sure TT/FT levels are not too low or high which could lead to lack of relief low-t symptoms/side-effects. Blood work is important and using accurate assays is critical. As you can see your trough TT sits in the 800s and your FT is high which would mean that your peak TT/FT levels will be much higher! Unfortunately you a relying on the calculated FT let alone we have no idea if your TT was tested using LC/MS-MS. The only way to know where your FT level truly sits on such protocol (dose T/injection frequency) is to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration. Let alone TT would need to be tested using (LC/MS-MS) even when using calculated methods. Regardless you can be rest assured that with a TT 800s and seeing as you have low SHBG 14 nmol/L that your FT will be high. If anything you should have labs done again and make sure to use the most accurate assays as you may be surprised that your FT level may very well be much higher than you think. When testing your FT either one will suffice! 1. [URL="https://www.discountedlabs.com/hematocrit-total-and-free-testosterone-1500-ng-dl"]Testosterone, Total and Free (NO Upper Limit) plus Hematocrit[/URL] 2. [URL="https://www.discountedlabs.com/testosterone-free-dialysis-and-total-ls-ms-ms"]Testosterone, Total, LC/MS and Free (Equilibrium Ultrafiltration)[/URL] I would also test your free estradiol (LC/MS-MS). [URL unfurl="true"]https://www.discountedlabs.com/free-estradiol-sensitive[/URL] From your post #10. [B]And for people who are curious... [U]yes I donate blood every 58 days. Hard to believe but I'm going for my 8th straight donation without skipping any additional days[/U]. I spoke to my Hematologist and asked him if this was safe? He said... he doesn't see anything wrong with it. So... [U]I donate 6 times a year. Yes, I feel like sh#$ for about 7-8 days (after each donation...) but... if you want to live... what else can you do[/U]?[/B] Not sure where your RBCs/hemoglobin/hematocrit sit on your current protocol (65 mg T E4D) but it is most likely high due to your high FT. Again even though your TT 800 may not seem absurdly high seeing as you have low SHBG 14 nmol/L you can rest assured that your FT is high. I would take a step back and think deeply on this as donating frequently is a surefire way to crash your ferritin. Many get caught up in that constantly donating merry go round to control hematocrit only to end up crashing ferritin/iron which can lead to many other issues. I would look into injecting more frequently as in daily or EOD using a lower dose of T. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
ED, No Libido, Seeing A Urologist Now
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