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General Health & Fitness
Health & Wellness
Ecdysteroids: Natural anabolic substance with no steroid side effects?
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<blockquote data-quote="Nelson Vergel" data-source="post: 103373" data-attributes="member: 3"><p>Ecdysteroids are hormonal compounds involved in the sexual behaviour of insects as well as molting and metamorphisis. Ecdysteroids share structural similarity to testosterone and are seen as the testosterone-like compound most active in insects. They are also present in plants to deter predators.</p><p></p><p>Ecdysteroids are widely marketed to athletes as dietary supplement,</p><p>advertising to increase strength and muscle mass during resistance</p><p>training, to reduce fatigue and to ease recovery. Several studies have</p><p>reported a wide range of pharmacological effects of ecdysteroids in</p><p>mammals, most of them beneficial to the organism. In the 1980s</p><p>the most active phytoecdysteroid, ecdysterone (beta-ecdysone, a</p><p>“Russian secret”), was suspected to be used by Russian Olympic</p><p>athletes. The levels of ecdysteroids in western diet are generally low</p><p>(usually in the range of less than 1 mg·day-1), while the doses used</p><p>by bodybuilders are stated in a range of up to 1000 mg·day-1.</p><p>Extensive investigations on the possible growth-promoting effects</p><p>of ecdysterone in various animal species (rats, mice, Japanese</p><p>quail and cattle) and in humans [1-13] were reported and lots of</p><p>rumors on its misuse by athletes are circulating since then. Ecdysterone</p><p>has been demonstrated to increase protein synthesis in</p><p>skeletal muscle [14]. Gorelick et al. proposed direct or indirect</p><p>stimulation of the PI3K/Akt signaling pathway as mechanism for</p><p>this increased protein synthesis [9, 15].</p><p></p><p>More information: <a href="https://examine.com/supplements/ecdysteroids/" target="_blank">Click here</a></p><p></p><p>Full Paper Attached</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 103373, member: 3"] Ecdysteroids are hormonal compounds involved in the sexual behaviour of insects as well as molting and metamorphisis. Ecdysteroids share structural similarity to testosterone and are seen as the testosterone-like compound most active in insects. They are also present in plants to deter predators. Ecdysteroids are widely marketed to athletes as dietary supplement, advertising to increase strength and muscle mass during resistance training, to reduce fatigue and to ease recovery. Several studies have reported a wide range of pharmacological effects of ecdysteroids in mammals, most of them beneficial to the organism. In the 1980s the most active phytoecdysteroid, ecdysterone (beta-ecdysone, a “Russian secret”), was suspected to be used by Russian Olympic athletes. The levels of ecdysteroids in western diet are generally low (usually in the range of less than 1 mg·day-1), while the doses used by bodybuilders are stated in a range of up to 1000 mg·day-1. Extensive investigations on the possible growth-promoting effects of ecdysterone in various animal species (rats, mice, Japanese quail and cattle) and in humans [1-13] were reported and lots of rumors on its misuse by athletes are circulating since then. Ecdysterone has been demonstrated to increase protein synthesis in skeletal muscle [14]. Gorelick et al. proposed direct or indirect stimulation of the PI3K/Akt signaling pathway as mechanism for this increased protein synthesis [9, 15]. More information: [URL="https://examine.com/supplements/ecdysteroids/"]Click here[/URL] Full Paper Attached [/QUOTE]
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General Health & Fitness
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Ecdysteroids: Natural anabolic substance with no steroid side effects?
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