E2 problem

phal

New Member
I am taking Testosterone Cyp 30 mg. 200mg T Cyp injected twice weekly.
I began taking T about a year ago around Christmas time.*

My problem is that I cannot get my E2 up where it belongs. I am always hovering around 15. My libido is dead and erections are soft.


I am on no AI all.
I am not on HCG.
10/23/2017 test results showed

TESTOSTERONE, TOTAL 1,051 ng/dL 221 - 716 ng/dL
FREE TESTOSTERONE CALCULATION 26.55 ng/dL 4.7 - 24.4 ng/dL
ALBUMIN 3.9 g/dL 3.5 - 5.0 g/dL
SEX HORMONE BINDING GLOBULIN 35.0 nmol/L 11 - 78 nmol/L

ESTRADIOL, SERUM 16 pg/mL 11 - 44 pg/mL

CBC:
WBC 10.09 10(3)/mcL 4.00 - 12.00 10(3)/mcL
RBC 5.61 10(6)/mcL 4.40 - 5.80 10(6)/mcL
HEMOGLOBIN (HGB) 17.1 g/dL 13.0 - 16.5 g/dL
HEMATOCRIT (HCT) 48.7 % 38.0 - 50.0 %
MCV 86.8 fL 82.0 - 96.0 fL
MCH 30.5 pg 26.0 - 32.0 pg
MCHC 35.1 g/dL 31.0 - 36.0 g/dL
PLATELET COUNT 186 10(3)/mcL 140 - 440 10(3)/mcL
RDW 12.3 % 11.8 - 15.5 %
MPV 10.9 fL 8.0 - 12.6 fL

I gave blood at the local center yesterday to get the Hematoocrit to a better level.

Any advice on what to do about the low E2? I feel great otherwise.*
Thanks.. Gary
 
Both HCG and DHEA can raise E2 in men. As with anything everyone reacts differently but either/both may be worth trying.
Unless I'm reading something wrong your Hematocrit did not look high?
 
Both HCG and DHEA can raise E2 in men. As with anything everyone reacts differently but either/both may be worth trying.
Unless I'm reading something wrong your Hematocrit did not look high?

The Hemocrit has been bouncing between 48 and 52, the blood donation was preventative medicine..
I had planned to begin hCG, maybe I should talk to the doc.
If that doesnt work, is DHEA availble over the counter? If so, what would be a starting dose?
Thanks
Gary
 
I personally take the HCG as do many here. Some Dr.s are reluctant but hopefully yours is not.
I am in Canada DHEA is not available over the counter here but it is in the USA. I am not taking it but the common dose seems to be 25mg.
 
For HCG the minimum is typically 250iu twice per week and the max is typically 500iu three time per week. Start at 250 and see how you feel. It'll likely raise your total T and free T so once you get your labs after being on HCG for 6 weeks you may have to reduce your Test Cyp dosage to compensate for the added HCG.
 
Based on the reference range, it appears you are testing estradiol with the incorrect test. Men should have their e2 measured with the sensitive/ultra-sensitive, LC, MS/MS, lab. That means your estradiol levels may be even lower than the value you presented.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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