E2 Levels in Healthy Young Men

[Saul]

Anyone seen data on E2 sensitive test levels in healthy young men? If they have high T levels, and T converts to E2, it would be interesting to know their E2 levels. Seems like easy data to get - just a blood test.

 

[Sean Mosher]

Don't have any data, but I will say that listening to a podcast yesterday by Jay Campbell with Dr. Rob Kominiarek, I believe he said something in the range of 60-80.
Again, I'm trying to recall from memory.
But his philosophy is to mainly treat symptoms and not numbers hardly at all.
He was also encouraging guys to get a baseline hormone panel done earlier in life, say the 20's, when you're feeling great to get an idea of where your numbers need to be in order to be optimized.

 

[Saul]

Thanks Sean. With people concerned about AI in the 40's I was wondering if that is normal for higher T levels, such as with young health males.

 

[strum]

Not exactly sure what you are asking but in any man, if there are high T levels or a testosterone surge it is fairly routine to see aromatization of T to E2 (estradiol). And that is not something you wish to ignore since estrogen will stimulate prolactin production (PRL) and PRL has many undesirable side effects in men. In adolescents going through puberty the testosterone surge often results in gynecomastia that can be very upsetting to a 13 year old boy. It will disappear over time as the hormone levels balance out. With men on TRT (testo replacement) inhibiting aromatization is very important. Same with men with prostate cancer being treated only with an anti-androgen, which will cause reflex increase in T leading to increase in E2.

 

[lowe2sucks]

^I've always noticed when you control aromatase too agressively trt isn't working nearly as good because estrogen enchances the way testosterone works particularly the antidepressant effect testosterone has it needs estrogen. its important to approach this situation as "e2 is good but too much is bad" but not as "e2 is waste product that needs to be supressed as much as possible" and there should be some guidelines what is too much estrogen.. i think folks who try to have their e2 in low 20s with test level of 900+ are doing more harm then good
many folks view trt as anti aging but if your trt keeps your e2 levels too low you will feel all knids of body aches, elbow pains and joint problems, fatigue i don't understand how its anti aging

 

[Vince]

Doctors have told me, that it would be nice to have a testosterone panel when you are young and feeling your best. Then you would know what your idea levels really are.