I'm one that sells the position that your E2 trough might need to mirror that SHBG value. This made a lot of difference for me. I have real positive progress when my E2 is in the single digits (trough). My body acne has cleared, sensitivity improved, orgasm is much better, lots of positives. Short of some erection issues that persist I'd be extremely happy.
I've too made the suggestion that maybe E2 should be managed from the peak, instead.
My Free Estrogen I've seen double to over the lab range @ 12hrs post injection on 14mg/D and that's with .25mg/D, too.
I over aromatase for no reason and I'm very sensitive to even a little too much E.
you have to keep in mind that E follows T, if you're looking at the trough alone thats just a low point...where is your PEAK?
We too know that SHBG binds E just like it does T, you could reasonably presume that if your Free T is over the lab range that your estrogen is following.
When guys say that they're doing great on X level of Estrogen you always have to account that the sides that they MAY be experiencing just aren't that problematic, to them. For me being hot and overly warm in bed at night doesn't sound all that bad, but it disrupts my sleep for hours and that's intolerable, for ME.
