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It is unlikely but not unheard of to have symptoms from a single dose 0.125 dose of anastrozole. There are multiple reports from forum members that this happened to them. But it also depends what your E2 was before you took it.


The drug itself can have side effects as well, so feeling like crap may not be due to decreased E2, but a direct drug side effect.


You have not specified what you symptoms nor E2 blood levels were related to this event. "Feel like complete shit" is not indicative of anything specific.


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