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Drinking Water and Diabetes: An Association in One Canadian Province
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<blockquote data-quote="CoastWatcher" data-source="post: 99124" data-attributes="member: 2624"><p>Higher concentrations of arsenic and fluoride in the public drinking water supply in Newfoundland and Labrador may be associated with the high incidence of type 1 diabetes in the Canadian province, according to findings published in <em>BMJ Open Diabetes Research & Care.</em></p><p><em></em></p><ul> <li data-xf-list-type="ul">Newfoundland and Labrador has the second highest incidence <a href="https://www.healio.com/endocrinology/diabetes/news/in-the-journals/%7b1632e80f-36eb-4ac2-a6e4-4ce14f446edc%7d/infection-risks-may-increase-with-type-1-diabetes" target="_blank">rate of type 1 diabetes</a> in the world after Finland, with an incidence rate of 49.9 per 100,000 for children during the 2007-2010 period. The highest incidence during 2007-2010 was among children aged 5 to 9 years, they noted, with an incidence rate ratio of 59.1 for that age group.</li> <li data-xf-list-type="ul"><strong>"There is accumulating evidence that drinking-water ingredients may be implicated in the environmental exposures contributing to the pathogenesis and progression of type 1 diabetes,” Chafe and colleagues wrote. “Newfoundland and Labrador has one of the highest reported incidences of type 1 diabetes worldwide, and the reasons for these high rates are unknown. The rates of type 1 diabetes are increasing in the province.”</strong></li> <li data-xf-list-type="ul">In a community-based, case-control study, the authors analyzed longitudinal data on the incidence rates of type 1 diabetes in 240 communities with a single public water supply monitored by the Provincial Department of Environment and Climate Change between 2000 and 2012.</li> <li data-xf-list-type="ul">Water quality for each community was averaged during the sampling period to produce one representative value for 21 nutrients and metals and eight major ions, including <a href="https://www.healio.com/endocrinology/cardiometabolic-disorders/news/in-the-journals/%7b998b68d0-3749-4370-8316-bc5347033bda%7d/low-level-arsenic-exposure-may-impair-insulin-sensitivity" target="_blank">arsenic</a>, fluoride, barium and nickel.</li> <li data-xf-list-type="ul">Cases of type 1 diabetes, identified using the Newfoundland and Labrador Pediatric Diabetes Database, were assigned to communities based on self-reported place of residence at the time of diagnosis. Cases occurring in communities not supplied by public water were excluded.</li> <li data-xf-list-type="ul">Researchers observed 499 cases of type 1 diabetes between 2001 and 2012, for an incident rate of 51.7 per 100,000 people for the province during the study period, with 87% of cases occurring in 114 communities serviced by the public water supply.</li> <li data-xf-list-type="ul">In these communities, the concentration of water nutrients and metals, including ammonia, barium, copper, lead, magnesium, uranium and zinc, were higher vs. communities without diabetes cases, according to researchers.</li> </ul><p></p><p>"Drinking water linked to high type 1 diabetes rate in Canadian province," Helio, 23 February 2018, <a href="https://www.healio.com/endocrinology/diabetes/news/in-the-journals/%7Bfd47c563-fb04-48cc-a4a6-4b1899ea7676%7D/drinking-water-linked-to-high-type-1-diabetes-rate-in-canadian-province" target="_blank">https://www.healio.com/endocrinology/diabetes/news/in-the-journals/{fd47c563-fb04-48cc-a4a6-4b1899ea7676}/drinking-water-linked-to-high-type-1-diabetes-rate-in-canadian-province</a></p></blockquote><p></p>
[QUOTE="CoastWatcher, post: 99124, member: 2624"] Higher concentrations of arsenic and fluoride in the public drinking water supply in Newfoundland and Labrador may be associated with the high incidence of type 1 diabetes in the Canadian province, according to findings published in [I]BMJ Open Diabetes Research & Care. [/I] [LIST] [*]Newfoundland and Labrador has the second highest incidence [URL="https://www.healio.com/endocrinology/diabetes/news/in-the-journals/%7b1632e80f-36eb-4ac2-a6e4-4ce14f446edc%7d/infection-risks-may-increase-with-type-1-diabetes"]rate of type 1 diabetes[/URL] in the world after Finland, with an incidence rate of 49.9 per 100,000 for children during the 2007-2010 period. The highest incidence during 2007-2010 was among children aged 5 to 9 years, they noted, with an incidence rate ratio of 59.1 for that age group. [*][B]"There is accumulating evidence that drinking-water ingredients may be implicated in the environmental exposures contributing to the pathogenesis and progression of type 1 diabetes,” Chafe and colleagues wrote. “Newfoundland and Labrador has one of the highest reported incidences of type 1 diabetes worldwide, and the reasons for these high rates are unknown. The rates of type 1 diabetes are increasing in the province.”[/B] [*]In a community-based, case-control study, the authors analyzed longitudinal data on the incidence rates of type 1 diabetes in 240 communities with a single public water supply monitored by the Provincial Department of Environment and Climate Change between 2000 and 2012. [*]Water quality for each community was averaged during the sampling period to produce one representative value for 21 nutrients and metals and eight major ions, including [URL="https://www.healio.com/endocrinology/cardiometabolic-disorders/news/in-the-journals/%7b998b68d0-3749-4370-8316-bc5347033bda%7d/low-level-arsenic-exposure-may-impair-insulin-sensitivity"]arsenic[/URL], fluoride, barium and nickel. [*]Cases of type 1 diabetes, identified using the Newfoundland and Labrador Pediatric Diabetes Database, were assigned to communities based on self-reported place of residence at the time of diagnosis. Cases occurring in communities not supplied by public water were excluded. [*]Researchers observed 499 cases of type 1 diabetes between 2001 and 2012, for an incident rate of 51.7 per 100,000 people for the province during the study period, with 87% of cases occurring in 114 communities serviced by the public water supply. [*]In these communities, the concentration of water nutrients and metals, including ammonia, barium, copper, lead, magnesium, uranium and zinc, were higher vs. communities without diabetes cases, according to researchers. [/LIST] "Drinking water linked to high type 1 diabetes rate in Canadian province," Helio, 23 February 2018, [URL]https://www.healio.com/endocrinology/diabetes/news/in-the-journals/%7Bfd47c563-fb04-48cc-a4a6-4b1899ea7676%7D/drinking-water-linked-to-high-type-1-diabetes-rate-in-canadian-province[/URL] [/QUOTE]
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Drinking Water and Diabetes: An Association in One Canadian Province
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