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Doctor and Clinic Reviews
Dr. Thierry Hertoghe
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<blockquote data-quote="electrify" data-source="post: 268537" data-attributes="member: 44439"><p>Yea it did, back in Feb/Mar 2018. I dont recall exactly but it was like 12 or so sessions. I remember with unilateral was first 6 and that mainly helped anxiety a lot but I needed bilateral and after the 2nd bilateral coming home sleeping and waking up like a switching was flipped. Then I needed a few more to make it stick. My symptoms were basically akin to severe PSSD/PFS just from 1 injection of 200 mcg. The thing was hell for my body. In 2 hours got severe anhedonia with the hard on. And constant severe nausea and agitation.</p><p></p><p>Was recommended ECT because when my normal doc (not Dr M) put me on nortrip it just blunted me more, abilify made me restless He then said “all med reactions are unpredictable just do ECT”. My doc had PFS/PSSD patients for whom it worked for and thought it would work for this too. And I was desperate so I did and it paid off. I ended up with just some foggy memory of the time I got it but otherwise cognitively I was totally fine in a month, and back to grad school in 2 weeks.</p><p></p><p>The first ECT center I tried called me bipolar psychotic for injecting PT141 and said I needed to be injected antipsychotics not ECT. So I tried another place and they were willing</p><p></p><p>Even still that year I would have random dips but I would take a Klonopin+Modafinil to kinda reset them. Post orgasm id still feel kinda blunted too for like a day but over time this resolved. The worst crash was when I smoked weed (indica strain) once and it just completely numbed me, a reaction I never had prior to PT141. Thankfully subsided in a week. I completely swore off all drugs after that outside social drinking and caffeine. I was fine from 2018-aug 2022, basically 4 years no issues.</p><p></p><p>However now years later in 2022 last year the 2 drugs (alcohol and caffeine) that were ok suddenly became problematic too. In july 2022 I got covid and I was fine but then in August a fucking alcohol hangover retriggered anhedonia that never happened before. I was recovering in a week but then guess what caffeine crashed me suddenly emotionally blunted me and I became sensitive to anything noradrenergic since. Although pure dopamine or precursors are ok, and armodafinil helps a bit but has tolerance. Thankfully my anhedonia is just moderate-mild this time, and doing monthly cycles of MIF-1 seems to help me.</p><p></p><p>Turns out I have dysbiosis too. But hormonally things are still fine. They did get impacted by the stress of this problem but changes in TRT dont affect my symptoms either way.</p><p></p><p>So yea PT141 seems to have permanently planted a vulnerability to anhedonia.</p><p></p><p>It pisses me off so much and its why im so triggered and get kind of “passionate” about anhedonia symptoms. Its quite possibly the worst condition imo to have, and having simple hormonal HPA low mood/anxiety issues is nothing in comparison. And few doctors even understand anhedonia-blunting as its own condition.</p><p></p><p>Dr M was not helpful at all for anhedonia.</p><p></p><p>It also surprises me how much can induce anhedonia in vulnerable people, even Ashwagandha or NAC can do it. On this forum I even read of Tamoxifen or Arimidex doing it. Ironically, TRT despite all the scare stories turns out to be safer than all this in terms of not having this side effect.</p></blockquote><p></p>
[QUOTE="electrify, post: 268537, member: 44439"] Yea it did, back in Feb/Mar 2018. I dont recall exactly but it was like 12 or so sessions. I remember with unilateral was first 6 and that mainly helped anxiety a lot but I needed bilateral and after the 2nd bilateral coming home sleeping and waking up like a switching was flipped. Then I needed a few more to make it stick. My symptoms were basically akin to severe PSSD/PFS just from 1 injection of 200 mcg. The thing was hell for my body. In 2 hours got severe anhedonia with the hard on. And constant severe nausea and agitation. Was recommended ECT because when my normal doc (not Dr M) put me on nortrip it just blunted me more, abilify made me restless He then said “all med reactions are unpredictable just do ECT”. My doc had PFS/PSSD patients for whom it worked for and thought it would work for this too. And I was desperate so I did and it paid off. I ended up with just some foggy memory of the time I got it but otherwise cognitively I was totally fine in a month, and back to grad school in 2 weeks. The first ECT center I tried called me bipolar psychotic for injecting PT141 and said I needed to be injected antipsychotics not ECT. So I tried another place and they were willing Even still that year I would have random dips but I would take a Klonopin+Modafinil to kinda reset them. Post orgasm id still feel kinda blunted too for like a day but over time this resolved. The worst crash was when I smoked weed (indica strain) once and it just completely numbed me, a reaction I never had prior to PT141. Thankfully subsided in a week. I completely swore off all drugs after that outside social drinking and caffeine. I was fine from 2018-aug 2022, basically 4 years no issues. However now years later in 2022 last year the 2 drugs (alcohol and caffeine) that were ok suddenly became problematic too. In july 2022 I got covid and I was fine but then in August a fucking alcohol hangover retriggered anhedonia that never happened before. I was recovering in a week but then guess what caffeine crashed me suddenly emotionally blunted me and I became sensitive to anything noradrenergic since. Although pure dopamine or precursors are ok, and armodafinil helps a bit but has tolerance. Thankfully my anhedonia is just moderate-mild this time, and doing monthly cycles of MIF-1 seems to help me. Turns out I have dysbiosis too. But hormonally things are still fine. They did get impacted by the stress of this problem but changes in TRT dont affect my symptoms either way. So yea PT141 seems to have permanently planted a vulnerability to anhedonia. It pisses me off so much and its why im so triggered and get kind of “passionate” about anhedonia symptoms. Its quite possibly the worst condition imo to have, and having simple hormonal HPA low mood/anxiety issues is nothing in comparison. And few doctors even understand anhedonia-blunting as its own condition. Dr M was not helpful at all for anhedonia. It also surprises me how much can induce anhedonia in vulnerable people, even Ashwagandha or NAC can do it. On this forum I even read of Tamoxifen or Arimidex doing it. Ironically, TRT despite all the scare stories turns out to be safer than all this in terms of not having this side effect. [/QUOTE]
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Doctor and Clinic Reviews
Dr. Thierry Hertoghe
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