A new study finds low testosterone and obesity independently affect all cause mortality.
A total of 948 participants aged ≥ 20 years old with endogenous sex hormones and adiposity measurements data were included in this study. Over a median of 9.5 y of follow-up, 142 men died of any cause in this cohort. Multivariable analysis showed a 2.60 fold increased risk of death among men with TD [testosterone deficiency] compared with men without TD. No evidence for interaction between TD and overall or abdominal obesity with risk of death. However, only after comparing men with TD and abdominal obesity with men without TD and no abdominal obesity, we found a 3.30 fold increased risk of death.