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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Does anyone use Nandrolone (Deca Durabolin) ?
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<blockquote data-quote="madman" data-source="post: 114365" data-attributes="member: 13851"><p>Nandrolone could never replace testosterone solely for trt as testosterones metabolites, dht and e2 are needed and play a critical role in the overall effectiveness of testosterone in men.</p><p></p><p>Sure there is still some aromatization with nandrolone and it is said to be roughly 20% of that compared to testosterone but it has never been proven in humans that it is only 20% and the biggest downfall is that nandrolone does not convert to dht (dihydrotestosterone) and converts to dhn (dihydronandrolone) which becomes less androgenic when attached to the AR (androgen receptor) as oppose to more androgenic effect of dht (dihydrotestosterone).</p><p></p><p>Testsosterones metabolites dht and estradiol are needed in healthy amounts and have beneficial effects regarding (mood/libido/erectile function/bone health).</p><p></p><p>On the other side of the coin as far as testosterones possible androgenic side effects related to dht such as ( excess oily skin/acne, male pattern baldness (in the genetically prone), excess body hair ) nandrolones metabolite dhn (dihydronandrolone) due to being less androgenic it is much less prone to causing these side effects in men.</p><p></p><p>As far as testosterone and negative side effects related to its metabolites dht and estradiol it is not common on trt doses mind you high e2 can be an issue for some but in a majority of men it would be from having too high free t and as far as oily skin/acne or male pattern baldness ones genetics plays a big factor and it comes down to the sensitivity of ones AR (androgen receptor).</p><p></p><p>Yes even on trt doses in the genetically sensitive prone individuals oily skin/acne and male pattern baldness can happen but it is not common.</p><p></p><p>I definitely agree that nandrolone is less androgenic and would be a good addition to a trt protocol for specific purposes but it could never replace testosterone for sole use as hormone replacement therapy.</p><p></p><p>Nandrolone is a better pure muscle tissue (actin/myosin) builder than testosterone and it has beneficial effects on the joints but in higher doses it has been shown to have a negative effect on lipids and possible negative effects on cardiovascular health (animal studies).</p><p></p><p>Unfortunately a majority of the research with nandrolone has been done using animals and the minimal research in humans is related to HIV/cancer.</p></blockquote><p></p>
[QUOTE="madman, post: 114365, member: 13851"] Nandrolone could never replace testosterone solely for trt as testosterones metabolites, dht and e2 are needed and play a critical role in the overall effectiveness of testosterone in men. Sure there is still some aromatization with nandrolone and it is said to be roughly 20% of that compared to testosterone but it has never been proven in humans that it is only 20% and the biggest downfall is that nandrolone does not convert to dht (dihydrotestosterone) and converts to dhn (dihydronandrolone) which becomes less androgenic when attached to the AR (androgen receptor) as oppose to more androgenic effect of dht (dihydrotestosterone). Testsosterones metabolites dht and estradiol are needed in healthy amounts and have beneficial effects regarding (mood/libido/erectile function/bone health). On the other side of the coin as far as testosterones possible androgenic side effects related to dht such as ( excess oily skin/acne, male pattern baldness (in the genetically prone), excess body hair ) nandrolones metabolite dhn (dihydronandrolone) due to being less androgenic it is much less prone to causing these side effects in men. As far as testosterone and negative side effects related to its metabolites dht and estradiol it is not common on trt doses mind you high e2 can be an issue for some but in a majority of men it would be from having too high free t and as far as oily skin/acne or male pattern baldness ones genetics plays a big factor and it comes down to the sensitivity of ones AR (androgen receptor). Yes even on trt doses in the genetically sensitive prone individuals oily skin/acne and male pattern baldness can happen but it is not common. I definitely agree that nandrolone is less androgenic and would be a good addition to a trt protocol for specific purposes but it could never replace testosterone for sole use as hormone replacement therapy. Nandrolone is a better pure muscle tissue (actin/myosin) builder than testosterone and it has beneficial effects on the joints but in higher doses it has been shown to have a negative effect on lipids and possible negative effects on cardiovascular health (animal studies). Unfortunately a majority of the research with nandrolone has been done using animals and the minimal research in humans is related to HIV/cancer. [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Does anyone use Nandrolone (Deca Durabolin) ?
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