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I've recently been considering TRT because of my low blood test results at age 40 (372 and 282), but in a month of scouring the internet, reading this forum, reading blogs, etc., it seems like a majority of TRT users experience ultimately ends up in some way negative for whatever reason?  The trend seems to be that people start off pretty well, but have diminishing returns and return of similar symptoms, and by 6 months want to try cycling off, but then have withdrawals or other issues that push them back into continuing? Either than or complaining of side effects that ultimately don't make TRT worth it.


Is this just a phenomenon of "only people with bad effects post about it on the internet", or has anyone else noticed this to be the case? Given that my levels are not on the absolute extreme end of low, I'm really concerned that I'm getting into something I will regret. Sometimes it is easy to read a few stories here and there about how awesome guys feel with TRT, curing the fatigue and depression fog they've had for years, and buy into it without considering what seems like a majority of wishy-washy experiences. The blogs and success stories I've read always seem to be by newer TRT users, and/or somehow related to marketing toward various online retailers, and that doesn't easily pass the smell test for me.


Where are all the guys talking about how great it has been for them, other than maybe Joe Rogan?


Thanks!


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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