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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
DEHYDROEPIANDROSTERONE (DHEA) AS A TREATMENT FOR ERECTILE DYSFUNCTION
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<blockquote data-quote="madman" data-source="post: 127857" data-attributes="member: 13851"><p>Much more involved when it comes to libido/ed.....multifaceted.</p><p></p><p></p><p><strong><span style="color: rgb(184, 49, 47)">Endocrinologic Control of Men’s Sexual Desire and Arousal/Erection </span></strong></p><p></p><p></p><p></p><p></p><p><strong>DHEA and Other Adrenal Hormones</strong></p><p></p><p>Past evidence documented a possible role of an agedependent decrease of DHEAS in the pathogenesis of ED.42,43 The MMAS found that DHEAS was the only hormone negatively correlated to the prevalence of ED among 17 investigated hormones, including T and E2.91 In addition, Basar et al,92 in a consecutive series of 348 men, reported that DHEAS and free T levels were significantly lower in men with sexual dysfunction as determined by the IIEF score. However, more recent data have advocated against an association between DHEA (and its DHEAS) and ED. A large placebo-controlled RCT evaluating the effect of DHEA in elderly men and women with an observational period up to 2 years failed to demonstrate a physiologically relevant beneficial effect on ED.93 Similarly, Morales et al94 reported that DHEA treatment (50 mg twice daily) did not induce significant differences in sexual performance outcomes compared with placebo as assessed by the IIEF, the Androgen Deficiency in the Aging Male questionnaire, the Aging Male Symptom Scale, and the Global Assessment Questionnaire. Similarly a meta-analysis evaluating the effect of DHEA administration in elderly men indicated that DHEA supplementation did not improve the overall score of the IIEF-15 or EF domain total score.45</p><p></p><p>The prevalence of ED in patients with Cushing syndrome is unknown. In particular, no information has been reported in the European Registry on Cushing’s Syndrome.47 Granata et al44 found that in subjects with adrenal insufficiency, treatment with glucocorticoids and mineralocorticoids independently improved the EF domain of the IIFF.</p><p></p><p><strong>RECOMMENDATION 10</strong></p><p></p><p> <strong><span style="color: rgb(184, 49, 47)">DHEA and DHEAS are not involved in the regulation of male EF (level 2A).</span></strong></p><p></p><p> Glucocorticoid and mineralocorticoid in adrenal insufficiency might play a role in restoring EF (level 4C). Prolactin</p></blockquote><p></p>
[QUOTE="madman, post: 127857, member: 13851"] Much more involved when it comes to libido/ed.....multifaceted. [B][COLOR=rgb(184, 49, 47)]Endocrinologic Control of Men’s Sexual Desire and Arousal/Erection [/COLOR][/B] [B]DHEA and Other Adrenal Hormones[/B] Past evidence documented a possible role of an agedependent decrease of DHEAS in the pathogenesis of ED.42,43 The MMAS found that DHEAS was the only hormone negatively correlated to the prevalence of ED among 17 investigated hormones, including T and E2.91 In addition, Basar et al,92 in a consecutive series of 348 men, reported that DHEAS and free T levels were significantly lower in men with sexual dysfunction as determined by the IIEF score. However, more recent data have advocated against an association between DHEA (and its DHEAS) and ED. A large placebo-controlled RCT evaluating the effect of DHEA in elderly men and women with an observational period up to 2 years failed to demonstrate a physiologically relevant beneficial effect on ED.93 Similarly, Morales et al94 reported that DHEA treatment (50 mg twice daily) did not induce significant differences in sexual performance outcomes compared with placebo as assessed by the IIEF, the Androgen Deficiency in the Aging Male questionnaire, the Aging Male Symptom Scale, and the Global Assessment Questionnaire. Similarly a meta-analysis evaluating the effect of DHEA administration in elderly men indicated that DHEA supplementation did not improve the overall score of the IIEF-15 or EF domain total score.45 The prevalence of ED in patients with Cushing syndrome is unknown. In particular, no information has been reported in the European Registry on Cushing’s Syndrome.47 Granata et al44 found that in subjects with adrenal insufficiency, treatment with glucocorticoids and mineralocorticoids independently improved the EF domain of the IIFF. [B]RECOMMENDATION 10[/B] [B][COLOR=rgb(184, 49, 47)]DHEA and DHEAS are not involved in the regulation of male EF (level 2A).[/COLOR][/B] Glucocorticoid and mineralocorticoid in adrenal insufficiency might play a role in restoring EF (level 4C). Prolactin [/QUOTE]
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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
DEHYDROEPIANDROSTERONE (DHEA) AS A TREATMENT FOR ERECTILE DYSFUNCTION
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