Any time I've called with an issue, it's resolved within the hour. The only reason it's not immediate is the person answering the phone is not a practitioner so it takes a bit to get one of them on the line. They also do quick e-mail consultations, although those might take a day or so to get an answer.
All in all, Defy goes above and beyond for their patients.
Hey, I've been shocked at how quickly they respond, even to emails.
I've worked in a medical office in the past and I am amazed at how well Defy takes care of things.