Daily subcutaneous testosterone for management of testosterone deficiency

madman

Super Moderator
54 men age range (26-82)

prescribed daily subcutaneous testosterone injection per DST Method

testosterone was administered as testosterone cypionate (7-18mg) in >95% of the patients included in the study

remaining patients recieved combination of testosterone cypionate/enanthate

testosterone was administerd subcutaneous injection using 30 gauge 1/2 inch hypodermic needle into outer thigh,biceps or gluteal muscle

hcg (220 units 2 days/week Monday and Friday) and anastrozole (once daily oral 0.25-0.5mg tablet) were also used during protocol

Would have been interesting to see the end results without the use of an aromatose inhibitor (anastrozole) and if the study was better controlled.

http://www.bioscience.org/2018/v10e/af/825/fulltext.php?bframe=2.htm
 
5. CONCLUSIONSDespite the noted limitations, the consistent and statistically significant increases in the three testosterone values suggest that the DST therapy method used for the patients included in the study has positive effects on testosterone level status. Co-treatment with an aromatase inhibitor and hCG appear to have prevented some of the adverse effects commonly observed with testosterone-only treatment. These findings can serve as a basis for further studies (including prospective controlled trials) to determine the range of benefits and better define the expected outcomes with the DST therapy method using aromatase inhibitor and hCG co-treatment.


Interesting study, I'm surprised that they injected in the thigh, biceps or gluteal muscle for a Sub-Q. It's nice to know the positive results with dailies.

 
All the study really shows was that T levels were increased by injecting Testosterone. Nothing about whether or not any of the subjects felt any better during treatment.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
0
Guests online
550
Total visitors
550

Latest posts

Back
Top