Current trends and therapies for chronic scrotal pain management

madman

Super Moderator
Abstract

The management of pain is a complex condition that will be encountered by most practicing clinicians. In the genitourinary community, testicular pain may be classified as acute or chronic. Initial evaluation of chronic groin and scrotal content pain (CGSCP) begins with a detailed history and physical examination to elucidate the presenting pathology. Multiple therapy algorithms have been proposed with no definitive consensus; however, most begin with conservative intervention and medical management prior to advancing to more invasive procedures. Surgical approaches may range from reconstruction, as in vasovasostomy for post-vasectomy pain syndrome, to excision of the offending agent, as in epididymectomy. This review seeks to focus on chronic pain in the genitourinary community and review techniques of pain management in the current intervention for orchialgia, as well as identify future methods of treatment.




Introduction

Orchialgia is a condition that has plagued the waiting rooms of clinicians from family practitioners, urologists, to internists. This review seeks to focus on chronic pain in the genitourinary community and review techniques of pain management in the current intervention for orchialgia, as well as identify future methods of treatment.




*History of pain management

*Orchialgia and the clinician

*Initial evaluation

*Pathophysiology

*Initial therapy


Selective nerve block
Epididymectomy
Varicocelectomy
Orchiectomy
Microsurgical denervation of the spermatic cord
Post-vasectomy pain



*Other therapies
Multiphoton microscopy
Ultrasound-guided targeted cryoablation of the perispermatic cord
Pulsed radiofrequency
Onabotulinum toxin





Conclusions

Chronic orchialgia is a complex condition that will be encountered by most practicing clinicians. When should a surgeon operate for scrotal pain? The short answer is that one should operate only when one has to. The goal is to operate less and on better-selected patients with more focused procedures. Testicular pain treatment should follow a systematic protocol that may be escalated to surgery when conservative therapy fails. Referral to adjunct specialties such as a chronic pain specialist, psychiatrist, physical therapist, or general surgeon may also be indicated.
 

Attachments

Figure 1. Initial workup and treatment algorithm for orchialgia. GABA, gamma-aminobutyric acid.
Screenshot (6227).webp
 

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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