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Does anyone know what the current Defy Medical restart protocol looks like? The most recent I could find was from 2021:

STOP T Cyp
BEGIN HCG 500 iu TIW x 2 weeks then stop
BEGIN Enclomiphene 25mg by mouth Daily M-F x 12 weeks then stop
CONT Anastrozole 0.2 mg twice weekly, discontinue at end of Enclomiphine cycle
Your next lab tests are due in 12 weeks
Testosterone, Free, Direct with Total Testosterone LabCorp
Estradiol, Sensitive (LC/MS) LabCorp
Luteinizing Hormone (LH) LabCorp
I have only been on TRT for a month prior to which I was on HCG mono-therapy for 2 months. I was not taking HCG while on TRT (Kyzatrex) for a month. I imagine both the HCG mono-therapy and the subsequent Kyzatrex would have been suppressive to my natural LH production.

Do I need a restart protocol as intense as the one listed above or whatever the most recent restart protocol is? If not, could Nelson, madman or any other veterans here offer some input on what might be a suitable restart protocol for me? Thanks a lot!

<blockquote data-quote="Ethan@50" data-source="post: 284200" data-attributes="member: 47042">Does anyone know what the current Defy Medical restart protocol looks like?&nbsp; The most recent I could find was from 2021:<ul>
<li data-xf-list-type="ul">STOP T Cyp</li>
<li data-xf-list-type="ul">BEGIN HCG 500 iu TIW x 2 weeks then stop</li>
<li data-xf-list-type="ul">BEGIN <a href="https://www.maximustribe.com/testosterone/enclomiphene?utm_source=Display&amp;utm_medium=Banner&amp;utm_campaign=ExcelMale" target="_blank">Enclomiphene</a> 25mg by mouth Daily M-F x 12 weeks then stop</li>
<li data-xf-list-type="ul">CONT Anastrozole 0.2 mg twice weekly, discontinue at end of Enclomiphine cycle</li>
</ul>Your next lab tests are due in 12 weeks<ul>
<li data-xf-list-type="ul">Testosterone, Free, Direct with Total Testosterone LabCorp</li>
<li data-xf-list-type="ul">Estradiol, Sensitive (LC/MS) LabCorp</li>
<li data-xf-list-type="ul">Luteinizing Hormone (LH) LabCorp</li>
</ul>I have only been on TRT for a month prior to which I was on HCG mono-therapy for 2 months.&nbsp; I was not taking HCG while on TRT (Kyzatrex) for a month.&nbsp; I imagine both the HCG mono-therapy and the subsequent Kyzatrex would have been suppressive to my natural LH production.&nbsp; Do I need a restart protocol as intense as the one listed above or whatever the most recent restart protocol is? If not, could Nelson, madman or any other veterans here offer some input on what might be a suitable restart protocol for me?&nbsp; Thanks a lot!</blockquote>

[QUOTE="Ethan@50, post: 284200, member: 47042"] Does anyone know what the current Defy Medical restart protocol looks like? The most recent I could find was from 2021: [LIST] [*]STOP T Cyp [*]BEGIN HCG 500 iu TIW x 2 weeks then stop [*]BEGIN [URL='https://www.maximustribe.com/testosterone/enclomiphene?utm_source=Display&utm_medium=Banner&utm_campaign=ExcelMale']Enclomiphene[/URL] 25mg by mouth Daily M-F x 12 weeks then stop [*]CONT Anastrozole 0.2 mg twice weekly, discontinue at end of Enclomiphine cycle [/LIST] Your next lab tests are due in 12 weeks [LIST] [*]Testosterone, Free, Direct with Total Testosterone LabCorp [*]Estradiol, Sensitive (LC/MS) LabCorp [*]Luteinizing Hormone (LH) LabCorp [/LIST] I have only been on TRT for a month prior to which I was on HCG mono-therapy for 2 months. I was not taking HCG while on TRT (Kyzatrex) for a month. I imagine both the HCG mono-therapy and the subsequent Kyzatrex would have been suppressive to my natural LH production. Do I need a restart protocol as intense as the one listed above or whatever the most recent restart protocol is? If not, could Nelson, madman or any other veterans here offer some input on what might be a suitable restart protocol for me? Thanks a lot! [/QUOTE]

Verification

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038