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Health & Wellness
COVID-19 and men’s health: What we know so far
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<blockquote data-quote="Nelson Vergel" data-source="post: 239009" data-attributes="member: 3"><p>Niger J Clin Pract. 2022 Nov;25(11):1812-1815. doi: 10.4103/njcp.njcp_188_22.</p><p></p><p><strong>Do the Covid-19 vaccines affect the reproductive parameters of men?-A Northern Saudi experience</strong></p><p></p><p>M J Alenzi 1, E E Ikpi 2, A S Alshlash 1, S M Alkhaldi 1, Z N Aljazi 1, M Alrawili 3, S Alanazi 4, J A Alenazi 3</p><p></p><p></p><p>PMID: 36412287 DOI: 10.4103/njcp.njcp_188_22</p><p></p><p>Abstract</p><p>Background: The COVID-19 vaccine acceptance is a psychological behavior influenced by many factors, including fear of an adverse effect on the reproductive system.</p><p></p><p>Aims: The aim of this study is to assess the COVID-19 vaccines effect on reproductive parameters among the male population of northern Saudi Arabia.</p><p></p><p>Patients and methods: We conducted a prospective cohort study among 100 volunteers who received two doses of COVID-19 vaccines. A pre- and post-vaccination blood sample was collected and analyzed for testosterone, prolactin, and follicle-stimulating hormone (FSH). Semen samples were also collected and analyzed. The Wilcoxon signed-rank test was used to compare the values between pre- and post-vaccination.</p><p></p><p>Results: Of the 100 samples analyzed, there was a significant increase in progressive sperm motility after the second dose of vaccination, but the increase was within the physiological limits (pre-55.03 [42.00-61.75] vs. post-57.50 [42.25-63.00], P = 0.008). Similarly, a significant increase in serum testosterone level after the second vaccination dose was observed (pre-380.65 [301.60-485.73] vs. post-410 [318.18-505.35], P = 0.016).</p><p></p><p><strong>Conclusion: These preliminary results show that the COVID-19 vaccines do not have any adverse effect on the reproductive parameters of men. A prospective long-term follow-up study will be necessary on all WHO -approved COVID vaccines to determine their long-term effect on men's reproductive health. The future follow-up study could strengthen our findings and encourage the men who have vaccine hesitancy to take due to fear of its effect on reproductive parameters.</strong></p><p></p><p>Keywords: COVID-19 vaccines; reproductive parameters; sperm count; testosterone.</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 239009, member: 3"] Niger J Clin Pract. 2022 Nov;25(11):1812-1815. doi: 10.4103/njcp.njcp_188_22. [B]Do the Covid-19 vaccines affect the reproductive parameters of men?-A Northern Saudi experience[/B] M J Alenzi 1, E E Ikpi 2, A S Alshlash 1, S M Alkhaldi 1, Z N Aljazi 1, M Alrawili 3, S Alanazi 4, J A Alenazi 3 PMID: 36412287 DOI: 10.4103/njcp.njcp_188_22 Abstract Background: The COVID-19 vaccine acceptance is a psychological behavior influenced by many factors, including fear of an adverse effect on the reproductive system. Aims: The aim of this study is to assess the COVID-19 vaccines effect on reproductive parameters among the male population of northern Saudi Arabia. Patients and methods: We conducted a prospective cohort study among 100 volunteers who received two doses of COVID-19 vaccines. A pre- and post-vaccination blood sample was collected and analyzed for testosterone, prolactin, and follicle-stimulating hormone (FSH). Semen samples were also collected and analyzed. The Wilcoxon signed-rank test was used to compare the values between pre- and post-vaccination. Results: Of the 100 samples analyzed, there was a significant increase in progressive sperm motility after the second dose of vaccination, but the increase was within the physiological limits (pre-55.03 [42.00-61.75] vs. post-57.50 [42.25-63.00], P = 0.008). Similarly, a significant increase in serum testosterone level after the second vaccination dose was observed (pre-380.65 [301.60-485.73] vs. post-410 [318.18-505.35], P = 0.016). [B]Conclusion: These preliminary results show that the COVID-19 vaccines do not have any adverse effect on the reproductive parameters of men. A prospective long-term follow-up study will be necessary on all WHO -approved COVID vaccines to determine their long-term effect on men's reproductive health. The future follow-up study could strengthen our findings and encourage the men who have vaccine hesitancy to take due to fear of its effect on reproductive parameters.[/B] Keywords: COVID-19 vaccines; reproductive parameters; sperm count; testosterone. [/QUOTE]
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