Could DIM have knocked my e2 too low?

[Mike9876]

Current Protocol:
110Mg pw Test Cyp
Injecting E2D

I've always only needed a very small amount of anastrozole. Having seen Dr Crisler and others talk about using DIM (Diindolylmethane) for years, I decided I would give this a try instead of the anastrozole. I've been taking 200mg of DIM (100mg morning, 100mg night) for about 5 weeks. In the past week or so I've started feeling pretty shitty. Anxiety and just not feeling good. As we know, pharmaceutical AI's can easily crash e2. My question is, is it possible the DIM has pushed my e2 too low? I have booked in for a blood test but where I live, sensitive estradiol results take about a week to come back so I'm looking for any advice others on here might have who've used or know about DIM.

 

[Cataceous]

DIM isn't supposed to lower the level of estradiol. Instead it affects the metabolic pathways controlling the disposition of estradiol. It gets pretty complicated, as "Kierkegaard" shows in this post:

How DIM Works, Yikes It Increases Aromatase, and Why I-3-C *Might* Be Better

How DIM Works, Yikes It Increases Aromatase, and Why I-3-C *Might* Be Better

www.peaktestosterone.com

 

[Vince]

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[Vince]

3,3′-Diindolylmethane Modulates Estrogen Metabolism in Patients with Thyroid Proliferative Disease: A Pilot Study - PMC

The incidence of thyroid cancer is four to five times higher in women than in men, suggesting a role for estrogen (E2) in the pathogenesis of thyroid proliferative disease (TPD) that comprises cancer and goiter. The objective of this study was to ...

www.ncbi.nlm.nih.gov

 

[Mike9876]

Thanks. I've read both those articles. I've pretty much determined from them that DIM isn't the best way to manage estrogen. If anyone has any further info on this or recommendations for the best ways to manage estrogen I'd love to hear them.