Clomid and ED

uvababb

New Member
Looking for some help. Here is my story, the short version.

Went to the doctor back in March of 2014 when i started having ED issues with the wife and lack of energy, brain fog. Physical came back normal but asked my old man doctor to check my T levels(will post labs further down). Of course that was the only thing he checked. I had him order panels below to hopefully cover everything.

age - 40
-height - 6'1
-waist - 40"
-weight - 240

-lab results with ranges -
Cholesterol: 250, range (110-200mg/dl) flagged as high
TRIG: 133, range (40 -149mg/dl)
HDL: 52, range (40-59mg/dl)
LDL: 171, range (50-99mg/dl) flagged as high
VLDL: 27, range (8-30mg/dl)
Glucose: 103, range (65-99mg/dl) flagged as high
BUN: 27, range (6-22mg/dl) flagged as high
MPV: 11.2, range (6.0-10.8) flagged as high

Vitamin D, 25 OH: 36.0, range (32.0-100ng/ml)

-My Testosterone was checked twice, once in PM and AM (had doctor
recheck b/c initially blood was done in the afternoon)
PM Overall Testosterone: 260, range(348-1197ng/dl) flagged as Low
PM testosterone free: 6.40, range(5.00-21.00ng/dl)
PM % free Testosterone: 2.46, range (1.50-4.20%)
AM Overall Testosterone: 326, range(348-1197ng/dl) flagged as Low
AM testosterone free: 6.59, range(5.00-21.00ng/dl)
AM % free Testosterone: 2.02, range (1.50-4.20%)

Estradiol: 11, range (8-43ng/l)
TSH: 2.15, range (0.27-4.20 MCU/ML)
T4: 5.7, range (4.5-10.9mcg/dl)
T3 Free, 2.3, range (2.3-4.2pg/ml)
SHBG: 27.3, range (16.5-55.9nmol/L)
Cortisol: 18.4, range (6.2-19.4mcg/dl)
FSH: 2.8, range (1.5-12.4 MIU/ML)
LH: 3.5, range (1.7-8.6 MIU/ML)
Prolactin: 10.4, range (4.0-15.2 NG/ML)

PSA: .48, range (< 1.400NG/ML)

So i went to a urologist who put me on 25mg of Clomid daily with 1 tablet of AI (anastrozole) weekly. I definitely started feeling a lot better and ED issues improved immensely. After about 3 months on the above protocol my labs were rechecked with the following positive results

FSH - 3.7 (0.9-15.0 mIU/mL)
LH - 3.1 (1.5- 9.3 mIU/mL)
E2 - 15 (11 - 44 pg/mL)
Testosterone - 668 (250 - 1000 ng/dl)
Sex Hormone Binding - 34 (11 - 78nmol/L)
[TABLE="class: cms_table"]
[TR="class: cms_table_odd"]
[TD="class: cms_table_infoCol"]Free Androgen Index - 68.1 (19.2 - 123.2)[/TD]
[TD="class: cms_table_importantCol"][/TD]
[/TR]
[TR]
[TD="class: cms_table_infoCol"]Testosterone Free - 145.0 (47.0 - 244.0 pg/ml)[/TD]
[TD="class: cms_table_importantCol"][/TD]
[/TR]
[TR="class: cms_table_odd"]
[TD="class: cms_table_importantCol"][/TD]
[/TR]
[TR]
[TD="class: cms_table_importantCol"]So after the results above the doc had me stay on the same protocol, no changes
25mg daily dosage of clomid and 1 tablet per week of anastrozole

Fast forward 3 months after that visit and the ED issues have started to reappear which deeply concerns me. I still feel good but def have been having trouble getting an erection for the wife. This is of course a big blow to my man hood. Also, im scheduled to see my doctor again in the next few weeks so any help would be appreciated.

Thanks
Mike
[/TD]
[/TR]
[/TABLE]
 

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Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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