Changing dosing schedule

intime

New Member
My doctor (for reasons that allude me) wanted me to try a bi weekly injection protocol instead of the weekly I had been doing.

I was using .5ml once a week. Last Sunday I switched to 1ml. It has now been 10 days and I don't like the trough and would like to return to my weekly schedule.

I was wondering what others thought would be the best option.

1) wait until the 14 days are up to return to my old dosing schedule

2) shoot .25ml now (10 days in) and then return to .5ml on my normal injection day

3) just shoot .5ml now and resume weekly dosing.

my only concerns with resuming too early are potential estradiol conversion, at the moment I do not have to take arimidex and I do not have any on hand.

Thanks so much!
 
Assuming that you are using testosterone cypionate or enanthate at 200 mg per ml, you can return to once a week injections as soon as you are due for the next shot. Most guys do not have ultrasensitive estradiol above 45 pg/mL even after 1-2 days of injecting 200 mg of testosterone. I would not worry too much but do get your E2 tested after a few weeks using the ultrasensitive assay.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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