Case of Stroke in a Steroid Using Young Man

Jinzang

Member
I thought this report was mildly interesting

The 28-year-old male patient presented with acute-onset vertigo, nausea, vomiting, and unsteady gait. The patient reported abusing testosterone and ********** for at least 6 years. He stated that he self-administered 325mg of testosterone every other day in addition to using an unspecified amount of **********. According to the study authors, magnetic resonance imaging of the patient's brain showed “small acute infarcts involving the left cerebellum and brainstem and was suggestive of an embolic pattern.” Laboratory findings revealed a total testosterone level of 2626ng/dL, a calculated free testosterone level of 5104pmol/L, and an estradiol level of 22.3pg/mL. Additional testing found elevated LDL and total cholesterol (TC) levels in addition to a low HDL level (LDL: 186mg/dL; TC: 225mg/dL; HDL: 18mg/dL). The patient's triglyceride level was normal (104 mg/dL). The patient was initiated on atorvastatin 80mg daily and was counseled on the discontinuation of exogenous testosterone.
 

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Predict estradiol, DHT, and free testosterone levels based on total testosterone

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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