Can Tamoxifen Decrease Libido?

dinhoguerra

New Member
I'm on TRT after a cycle with steroids. My protocol is 45mg Cypionate EOD. But, due to a principle of gynecomastia (in the cycle), I'm taking 60mg tamox ED.
My exames labs is all ok. TT > 1000 and E2 <50 .
However, I am felling with low libido. Morning woods are presents every day.
Can anyone help me?
P.s.: Excuse my english, it's not my language.
 
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If you only just started TRT it's going to take some time, erections and libido can take anywhere from 6-12 months to fully resolve. Also high E2 will lower libido, make sure you are using the Sensitive E2 tests LC/MS/MS method. We really need more labs than you are providing, including SHBG. If SHBG is lower, this protocol may be wrong for you.

How long have you been on this protocol?
 
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If you only just started TRT it's going to take some time, erections and libido can take anywhere from 6-12 months to fully resolve. Also high E2 will lower libido, make sure you are using the Sensitive E2 tests LC/MS/MS method. We really need more labs than you are providing, including SHBG.

How long have you been on this protocol?

Excuse-me, the correct number is 42
 
Maybe on low T, but with T > 1000?
Your Total T isn't the problem, estrogen levels may be. I know it would cause me problems with libido regardless of my Total T number. Your high Total T may be why E2 is high, we men convert testosterone into estrogen, the more testosterone, the higher the estrogen.

If you reduce your dosage, estrogen would decrease.
 
Remember the total is all bound up and doesn't really mean anything. Id be more inclined to make a point of the Estrogen if we knew the SHBG and Free T
 
Your SHBG of 16.5 tells me that your Estradiol needs to be much closer to that same number, 43.6 is likely to high for YOU the individuals. Notice how high your Free T is? This means the Free Estrogen is likewise very high. You should reduce your Testosterone dosing to get your Free T down closer but not too much over the lab range. Your E should come down that way.
 
I call tamoxifen = tamoxivenom. Amongst other terrible side effects it kills my libido. However very efficient to get rid of recent gyno (specially the lump type).
 
I call tamoxifen = tamoxivenom. Amongst other terrible side effects it kills my libido. However very efficient to get rid of recent gyno (specially the lump type).
Thanks for your response.
Did you use tamoxifen while on TRT?
How much time after stopping tamoxifen your libido came back?
 
Thanks for your response.
Did you use tamoxifen while on TRT?
How much time after stopping tamoxifen your libido came back?
I used Tamoxifen several times during TRT to combat gyno and during PCT/restarts. Keep in mind that tamoxifen has a long half life and its main metabolite has an even longer half life. So if i am not mistaken it might take ~8 weeks to have both tamoxifen and its main metabolite out of your system. So during the end of this period you should start to get your libido back (if indeed tamoxifen was what caused the low libido in the first place)
 
I used Tamoxifen several times during TRT to combat gyno and during PCT/restarts. Keep in mind that tamoxifen has a long half life and its main metabolite has an even longer half life. So if i am not mistaken it might take ~8 weeks to have both tamoxifen and its main metabolite out of your system. So during the end of this period you should start to get your libido back (if indeed tamoxifen was what caused the low libido in the first place)
 
I used Tamoxifen several times during TRT to combat gyno and during PCT/restarts. Keep in mind that tamoxifen has a long half life and its main metabolite has an even longer half life. So if i am not mistaken it might take ~8 weeks to have both tamoxifen and its main metabolite out of your system. So during the end of this period you should start to get your libido back (if indeed tamoxifen was what caused the low libido in the first place)
I've been reading some of your posts and it seems to me that you're quite sensitive to gynecomastia. Considering that you use tamoxifen to treat, how do you solve the libido problem during treatment?
 
I've been reading some of your posts and it seems to me that you're quite sensitive to gynecomastia. Considering that you use tamoxifen to treat, how do you solve the libido problem during treatment?
Symptoms were gone after 2 months with very noticeable improvement after 4 weeks
 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

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Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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