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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Can Methylene Blue cause erectile dysfunction?
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<blockquote data-quote="Guided_by_Voices" data-source="post: 255756" data-attributes="member: 15235"><p>Several things...1)The big-brains on MB (e.g. Fransisco Gonzalez-Lima) seem to suggest that for general benefit, intermittent low-dose use is the way to go. For example, I use less than 5 mg one or two times per week. 2) Nitric Oxide is a very complicated topic in itself and from what I understood of the podcasts I've heard from people who study it, it is another case where too much can be bad as well as too little. 3) My take away from a quick scan of the topic is that it's very unclear if it is even reducing NO in a meaningful way, let alone one that would affect erections 4) Other aspects of MB should have a positive affect on the endothelium in general and hence NO, such as enhanced cardio performance, and 5) MB seems to have so many net-benefits that the risk/reward seems firmly tilted toward reward, at least when used intermittently in low doses, similar to how rapamycin (and many other things like insulin) seem beneficial when used that way but likely harmful to an otherwise healthy person when used chronically in high doses.</p><p></p><p>Here's an example in the linked podcast of the complexity of the NO topic...</p><p></p><p>[URL unfurl="true"]https://podcasts.apple.com/us/podcast/shr-2202-b6-metabolism-nitric-oxide-stress-signaling/id1263638028?i=1000413585823[/URL]</p></blockquote><p></p>
[QUOTE="Guided_by_Voices, post: 255756, member: 15235"] Several things...1)The big-brains on MB (e.g. Fransisco Gonzalez-Lima) seem to suggest that for general benefit, intermittent low-dose use is the way to go. For example, I use less than 5 mg one or two times per week. 2) Nitric Oxide is a very complicated topic in itself and from what I understood of the podcasts I've heard from people who study it, it is another case where too much can be bad as well as too little. 3) My take away from a quick scan of the topic is that it's very unclear if it is even reducing NO in a meaningful way, let alone one that would affect erections 4) Other aspects of MB should have a positive affect on the endothelium in general and hence NO, such as enhanced cardio performance, and 5) MB seems to have so many net-benefits that the risk/reward seems firmly tilted toward reward, at least when used intermittently in low doses, similar to how rapamycin (and many other things like insulin) seem beneficial when used that way but likely harmful to an otherwise healthy person when used chronically in high doses. Here's an example in the linked podcast of the complexity of the NO topic... [URL unfurl="true"]https://podcasts.apple.com/us/podcast/shr-2202-b6-metabolism-nitric-oxide-stress-signaling/id1263638028?i=1000413585823[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Can Methylene Blue cause erectile dysfunction?
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