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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Best Way to Increase Semen ?
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<blockquote data-quote="Buffbanker" data-source="post: 138551" data-attributes="member: 15294"><p>Pygeum has worked well for me in addition to black maca and letchitin. Although I came across numerous studies on PubMed stating that two active ingredients are androgen receptor antagonists. Specifically, the compounds are able to displace a statistically significant amount of Testosterone and DHT at the AR receptor site. Therefore counteracting some of the benefits of TRT. Now I am a bit hesitant to use this again. In other in vitro studies it was found to also displace bound estrogen at the ER receptor. I had an abnormal sensitive E2 lab test at 277 pg/mL while taking Pygeum. I had a retest done since I suspected a lab error a week later and got a result of 58 pg/mL. So it’s possible that itbskewed the result. I have a follow lab Monday now that it has been a few weeks and should be completely out of my system to determine if Pygeum has more AR and ER agonist activity than we should be comfortable with while on TRT.</p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pubmed/20965230/" target="_blank">The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer c... - PubMed - NCBI</a></p><p></p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pubmed/19771394/" target="_blank">NBBS isolated from Pygeum africanum bark exhibits androgen antagonistic activity, inhibits AR nuclear translocation and prostate cancer cell growth. - PubMed - NCBI</a></p></blockquote><p></p>
[QUOTE="Buffbanker, post: 138551, member: 15294"] Pygeum has worked well for me in addition to black maca and letchitin. Although I came across numerous studies on PubMed stating that two active ingredients are androgen receptor antagonists. Specifically, the compounds are able to displace a statistically significant amount of Testosterone and DHT at the AR receptor site. Therefore counteracting some of the benefits of TRT. Now I am a bit hesitant to use this again. In other in vitro studies it was found to also displace bound estrogen at the ER receptor. I had an abnormal sensitive E2 lab test at 277 pg/mL while taking Pygeum. I had a retest done since I suspected a lab error a week later and got a result of 58 pg/mL. So it’s possible that itbskewed the result. I have a follow lab Monday now that it has been a few weeks and should be completely out of my system to determine if Pygeum has more AR and ER agonist activity than we should be comfortable with while on TRT. [URL="https://www.ncbi.nlm.nih.gov/pubmed/20965230/"]The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer c... - PubMed - NCBI[/URL] [URL="https://www.ncbi.nlm.nih.gov/pubmed/19771394/"]NBBS isolated from Pygeum africanum bark exhibits androgen antagonistic activity, inhibits AR nuclear translocation and prostate cancer cell growth. - PubMed - NCBI[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Best Way to Increase Semen ?
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