Dr Rotman
1- do you think DHT is a protagonist in PCa?
2- do you think estrogen is a protagonist in PCa?
3- what do you think is the reason as to why finasteride and dustasteride were associated with higher rates of Aggressive PCa in the trials ?
Hi, doctor.
I am 38 yo, healthy, have 2 kids, but last 2 years y have poor sexual drive and my analisis showed low test (total test 241 and free test 8) with the other parameters in normal range. I exercise 4 days a week, 1,80m and 80kg, with 13% bf. I started clomid 50mg ED two weeks ago, but no improve. I want to preserve fertility, but i think maybe i need TRT? What is your opinion, doctor? Thank you very much
Hi Gianluca,Hello Doc
I was a patience of your till about a year an half a go through LowT.com I find my self in NYC now and I need to do a therapeutic phlebotomy as my hematocrit is up at 51.1, unfortunately I can't donate, Do you know any place I could get that done?
thank you
If the clomid is not effective , there are other options including TRT while preserving fertility. Clomid frequently has a paradoxical effect.
Thanks, Dr Rotman Just one question, what do you mean by "paradoxical effect"? Can i do something like this protocol: TRT (sq injections of 100mg of testoviron two times/week) + 500 u.i. HCG 3 times a week? I saw some scientific articles sustaining this protocol. Thanks again !
DrRotmon, at what level do you become concerned with or treat estradiol?
Thrilled to see you participating here Dr Rotman! Keep it up, this is a great community only made better by physician participation.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.
Enter your total testosterone value to see predictions
Results will appear here after calculation
A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038