Arimidex/Anastrozole intolerant. Would Aromasin work?

[trt reznor]

I can’t even tolerate a 0.0625mg dose of Anastrozole, I don’t know if it crashes my E2 or if I just get a bad reaction to the drug, but it takes about 2 or 3 days to recover.

Has anyone had this issue and then had success with Aromasin?

 

[seb288]

You posted this a while ago, but I'll offer my two cents. I've had a lot of success with aromasin, but microdosed at 1/100 pill once a week. Studies have shown that 2.5mg has the same effect as 25 and 50mg. So I need even less than that.

As to whether it'll be a better choice, that depends - do you get a estrogen rebound with anastrozole? Where your E2 returns with a vengeance, or does it return to pre anastrozole baseline?

 

[trt reznor]

You posted this a while ago, but I'll offer my two cents. I've had a lot of success with aromasin, but microdosed at 1/100 pill once a week. Studies have shown that 2.5mg has the same effect as 25 and 50mg. So I need even less than that.

As to whether it'll be a better choice, that depends - do you get a estrogen rebound with anastrozole? Where your E2 returns with a vengeance, or does it return to pre anastrozole baseline?

Sorry for such a late reply, I never saw your post. But yes estrogen rebound is absolutely what gets me with arimidex, even the tiniest amount. Whats the cause of that?

 

[Vince]

Interrelations between sex hormone-binding globulin (SHBG), plasma lipoproteins and cardiovascular risk - PubMed

The incidence of coronary artery disease is significantly higher in men than in women, at least until menopause. This gender difference could be explained by the action of sex steroids on the lipoprotein profile. In prepubertal children, high-density lipoprotein (HDL) cholesterol and...

pubmed.ncbi.nlm.nih.gov

 

[seb288]

Sorry for such a late reply, I never saw your post. But yes estrogen rebound is absolutely what gets me with arimidex, even the tiniest amount. Whats the cause of that?

Sorry for such a late reply, I never saw your post and was rarely using the site. Arimidex is not a suicidal inhibitor, Aromasin is - so you won't get the rebound with Asin. But be careful - I don't lower my estrogen anymore - I am on 24.5mg of test per week and I also take daily injections of estradiol.