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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Appropriate Starting Dose for Propionate?
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<blockquote data-quote="Cataceous" data-source="post: 158188" data-attributes="member: 38109"><p>I think his estradiol levels aren't unusual for the amount of testosterone, and we are talking about borderline supraphysiological levels of testosterone. There's been an ongoing debate about the relative importance of absolute estradiol versus the ratio of testosterone to estradiol. I suspect that both parameters are important, perhaps affecting different things.</p><p></p><p>SHBG does bind estradiol, but which levels are you saying "build up," and why? My reasoning is based on a quasi-steady state that develops in a two-hour or so time frame. The assumption is that rate of testosterone excretion equals the rate of absorption. We control the absorption rate via injections. Free testosterone is the variable in excretion that must change to meet differing absorption rates brought about by different doses. Estradiol is in turn created from the free testosterone, probably in direct proportion.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 158188, member: 38109"] I think his estradiol levels aren't unusual for the amount of testosterone, and we are talking about borderline supraphysiological levels of testosterone. There's been an ongoing debate about the relative importance of absolute estradiol versus the ratio of testosterone to estradiol. I suspect that both parameters are important, perhaps affecting different things. SHBG does bind estradiol, but which levels are you saying "build up," and why? My reasoning is based on a quasi-steady state that develops in a two-hour or so time frame. The assumption is that rate of testosterone excretion equals the rate of absorption. We control the absorption rate via injections. Free testosterone is the variable in excretion that must change to meet differing absorption rates brought about by different doses. Estradiol is in turn created from the free testosterone, probably in direct proportion. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Appropriate Starting Dose for Propionate?
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